引用本文:
卓仁禧, 尹超, 吴颖楠, 祝磊, 曾水清. 聚乳酸眼科植入材料的制备及其降解性能[J]. 应用化学,
1997, 14(2): 102-104.
Citation: Zhuo Renxi, Yin Chao, Wu Yinnan, Zhu Lei, Zhen Shuiqing. Synthesis and Degradation Behavior of Poly (DL-Lactide) for Ophthalmic Application[J]. Chinese Journal of Applied Chemistry, 1997, 14(2): 102-104.
Citation: Zhuo Renxi, Yin Chao, Wu Yinnan, Zhu Lei, Zhen Shuiqing. Synthesis and Degradation Behavior of Poly (DL-Lactide) for Ophthalmic Application[J]. Chinese Journal of Applied Chemistry, 1997, 14(2): 102-104.
聚乳酸眼科植入材料的制备及其降解性能
English
Synthesis and Degradation Behavior of Poly (DL-Lactide) for Ophthalmic Application
Abstract:
The application of poly(DL-lactide)(PLA) as a biodegradable ophthalmic implant has been studied. The PLA was synthesized from DL-lactide by bulk ring-opening polymerization initiated by stannous 2-ethylhexanoate. Both the pressure of polymerization system and the mole ratio of monomer to initiator showed a marked influence on the relative molecular weights of PLA. The in vitro and in vivo degradation of PLA has been investigated in 0.2 mol/L Na2HPO4-NaH2PO4 solution in rabbit's eyes.
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Key words:
- polylactide
- / synthesis
- / biodegradation
- / ophthalmic implant
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