引用本文:
邓新旺, 胡惠媛, 罗仲宽, 吴茂盛, 周莉. 肝素钠/聚乙烯醇复合水凝胶的制备与性能[J]. 应用化学,
2015, 32(12): 1358-1363.
doi:
10.11944/j.issn.1000-0518.2015.12.150228
Citation: DENG Xinwang, HU Huiyuan, LUO Zhongkuan, WU Maosheng, ZHOU Li. Preparation and Properties of Heparin Sodium/Polyvinyl Alcohol Composite Hydrogel[J]. Chinese Journal of Applied Chemistry, 2015, 32(12): 1358-1363. doi: 10.11944/j.issn.1000-0518.2015.12.150228
Citation: DENG Xinwang, HU Huiyuan, LUO Zhongkuan, WU Maosheng, ZHOU Li. Preparation and Properties of Heparin Sodium/Polyvinyl Alcohol Composite Hydrogel[J]. Chinese Journal of Applied Chemistry, 2015, 32(12): 1358-1363. doi: 10.11944/j.issn.1000-0518.2015.12.150228
肝素钠/聚乙烯醇复合水凝胶的制备与性能
English
Preparation and Properties of Heparin Sodium/Polyvinyl Alcohol Composite Hydrogel
Abstract:
Heparin sodium/polyvinyl alcohol(HS/PVA) composite hydrogel was prepared successfully by the cyclic freezing-thawing method. Effects of mass fraction of heparin sodium on visible light transmittance,moisture content,hydrophilcity,mechanical property and percentage of heparin sodium release of composite hydrogel were studied. The results show that the introduction of heparin sodium into the structure of PVA can enhance the moisture content and hydrophilic of HS/PVA composite hydrogel,simultaneously,reduce visible light transmittance and mechanical properties of HS/PVA composite hydrogel. The release of heparin sodium from HS/PVA composite hydrogel resists the cell adhesion. Therefore,the HS/PVA composite hydrogel has a potential application in the fields of optical central materials of artificial cornea.
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Key words:
- heparin sodium
- / polyvinyl alcohol
- / composite hydrogel
- / artificial cornea
- / cell adhesion
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