Facile synthesis of 1-naphthols through a copper-catalyzed arylation of methyl ketones with o-bromoacetophenones

Zhen-Bang Lou Xin-Long Pang Chao Chen Li-Rong Wen Ming Li

Citation:  Zhen-Bang Lou, Xin-Long Pang, Chao Chen, Li-Rong Wen, Ming Li. Facile synthesis of 1-naphthols through a copper-catalyzed arylation of methyl ketones with o-bromoacetophenones[J]. Chinese Chemical Letters, 2015, 26(10): 1231-1235. doi: 10.1016/j.cclet.2015.07.022 shu

Facile synthesis of 1-naphthols through a copper-catalyzed arylation of methyl ketones with o-bromoacetophenones

    通讯作者: Chao Chen,
    Ming Li,
  • 基金项目:

    This work was supported by National Natural Science Foundation of China (Nos. 21102080, 21372138)  (Nos. 21102080, 21372138)

    Tsinghua University Initiative Scientific Research Program (No. 2011Z02150). (No. 2011Z02150)

摘要: The coupling reactions of simple methyl ketones with o-bromoacetophenones and subsquential cyclization reactions were realized to produce a range of 1-naphthols. These cascade reactions were initiated by a rare Cu-catalyzed arylation reaction of methyl ketones with aromatic bromides.

English

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  • 发布日期:  2015-07-29
  • 收稿日期:  2015-05-15
  • 网络出版日期:  2015-07-20
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