Liquid Chromatographic Resolution of Racemic 2-Phenyl-1,1-cyclo-propanedicarbonitrile and its Analogues on Chiral Stationary Phase

You Cheng LIU Xin Zhu LI Jing LI

引用本文: You Cheng LIU,  Xin Zhu LI,  Jing LI. Liquid Chromatographic Resolution of Racemic 2-Phenyl-1,1-cyclo-propanedicarbonitrile and its Analogues on Chiral Stationary Phase[J]. Chinese Chemical Letters, 2000, 11(4): 353-356. shu
Citation:  You Cheng LIU,  Xin Zhu LI,  Jing LI. Liquid Chromatographic Resolution of Racemic 2-Phenyl-1,1-cyclo-propanedicarbonitrile and its Analogues on Chiral Stationary Phase[J]. Chinese Chemical Letters, 2000, 11(4): 353-356. shu

Liquid Chromatographic Resolution of Racemic 2-Phenyl-1,1-cyclo-propanedicarbonitrile and its Analogues on Chiral Stationary Phase

  • 基金项目:

    Support from the National Natural Science Foundation of China is gratefully acknowledged.

摘要: Excellent resolution of racemic 2-phenyl-1,1-cyclopropanedicarbonitrile and its nine analogues was accomplished using 100-5CHI-TBB chiral stationary phase under normal-phase HPLC conditions. The influence of mobile phase and the optimum conditions for the resolution of optically active enantiomers were investigated.

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  • 收稿日期:  1999-11-03
  • 修回日期:  2000-01-03
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