磁性氧化石墨烯的制备及其在环境水样中7种内分泌干扰物检测中的应用

引用本文: 郭菁豪, 童裳伦. 磁性氧化石墨烯的制备及其在环境水样中7种内分泌干扰物检测中的应用[J]. 色谱, 2020, 38(5): 522-528. doi: 10.3724/SP.J.1123.2019.10007 shu

Citation: GUO Jinghao, TONG Changlun. Synthesis of magnetic graphene oxide modified with dodecylamine and its application for the determination of seven endocrine-disrupting chemicals in environmental water samples[J]. Chinese Journal of Chromatography, 2020, 38(5): 522-528. doi: 10.3724/SP.J.1123.2019.10007 shu

磁性氧化石墨烯的制备及其在环境水样中7种内分泌干扰物检测中的应用

郭菁豪 ,
童裳伦 ^,

浙江大学环境与资源学院, 浙江杭州 310058

通讯作者: 童裳伦, E-mail:cltong@zju.edu.cn

基金项目:
国家自然科学基金（21177105）.

摘要: 制备了十二胺修饰的磁性氧化石墨烯纳米材料并将其用于磁固相萃取。在对磁固相萃取材料合成与萃取条件以及液相色谱分离等条件进行优化的基础上，建立了磁固相萃取与高效液相色谱-紫外检测对环境水样中7种内分泌干扰物的分析方法。该方法对雌酮、雌二醇、雌三醇、双酚A、17α-乙炔基雌二醇、己烷雌酚和雄烯二酮7种内分泌干扰物的检出限在0.10~0.23 nmol/L之间。将该方法分别应用于废水样品和湖水样品的加标回收试验，回收率在73.9%~112.9%和74.9%~114.7%之间。该方法操作简便，分析成本较低，可为环境水体中内分泌干扰物的分析提供技术支持。

关键词:

English

Synthesis of magnetic graphene oxide modified with dodecylamine and its application for the determination of seven endocrine-disrupting chemicals in environmental water samples

GUO Jinghao ,
TONG Changlun ^,

College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China

Corresponding author: TONG Changlun, cltong@zju.edu.cn

Received Date: 08 October 2019
Fund Project:
National Natural Science Foundation of China (No. 21177105).

Abstract: Magnetic graphene oxide (MGO) modified with dodecylamine (DDA) was synthesized in this work. The as-prepared MGO-DDA was characterized by Fourier transform infrared spectroscopy, X-ray diffraction, and vibrating sample magnetometer measurements. The material was used as the absorbent in magnetic solid-phase extraction (MSPE) for seven environmental endocrine-disrupting chemicals (EDCs):estrone (E1), β-estradiol (E2), estriol (E3), 17α-ethynylestradiol (EE2), hexoestrol (HEX), androstendione (AND), and bisphenol A (BPA). MSPE combined with HPLC-UV was developed for the determination of EDCs in environmental water samples. The effects of the amount of adsorbent, adsorbing time, and the type and volume of eluents on the recoveries of the EDCs were investigated. Under the optimal conditions, good linear relationships between the UV signals and the EDC concentrations were obtained, with R² greater than 0.999. The limits of detection for all the EDCs were between 0.10 and 0.23 nmol/L. The MSPE-HPLC-UV method was successfully applied to the analysis of the seven EDCs in environmental water samples such as lake water and sewage water samples. The recoveries of all the EDCs in spiked lake water and sewage water samples were between 73.9% and 114.7%, and the RSDs ranged from 0.7% to 11.8%. Thus, the proposed MSPE-HPLC-UV method is simple, reliable, sensitive, and low-cost.

Key words:

1. [1] Shrestha S L, Casey F X, Hakk H, et al. Environ Sci Technol, 2012, 46(20):11047
2. [2] Harris C A, Hamilton P B, Runnalls T J, et al. Environ Health Persp, 2011, 119(3):306
3. [3] Combalbert S, Hernandez-Raquet G. Appl Microbiol Biotechnol, 2010, 86(6):1671
4. [4] Ding W J, Yuan T, Shen F, et al. Journal of Clinical Hepatology, 2018, 34(6):1268 丁雯瑾, 袁涛, 沈峰, 等. 临床肝胆病杂志, 2018, 34(6):1268
5. [5] Hua Y Y, Lin Q, Lu C Y. Physical Testing and Chemical Analysis (Part B:Chemical Analysis), 2019, 55(8):904 华永有, 林麒, 卢翠英. 理化检验(化学分册), 2019, 55(8):904
6. [6] Socas-Rodriguez B, Herrera-Herrera A V, Hernandez-Borges J, et al. J Chromatogr A, 2017, 1496:58
7. [7] Shang Y L, Zhao W J, Xu E C, et al. Biosens Bioelectron, 2010, 25:1056
8. [8] Deng Y L, Li A T, Wang Y F, et al. Chinese Journal of Chromatography, 2018, 36(3):253 邓玉兰, 李傲天, 王燕飞, 等. 色谱, 2018, 36(3):253
9. [9] Liu C, Chen L, Ye Z W, et al. Chinese Journal of Chromatography, 2019, 37(8):918 刘程, 陈蕾, 叶子雯, 等. 色谱, 2019, 37(8):918
10. [10] Peng S, Li H, Shi S Y. Chinese Journal of Chromatography, 2019, 37(3):293 彭胜, 李奂, 施树云. 色谱, 2019, 37(3):293
11. [11] Huang Q, He M, Chen B B, et al. Chinese Journal of Chromatography, 2014, 32(10):1131 黄倩, 何蔓, 陈贝贝, 等. 色谱, 2014, 32(10):1131
12. [12] Deng X J, Lü L L, Li H W, et al. J Hazard Mater, 2010, 183(1/2/3):923
13. [13] Wang H, Yuan X Z, Wu Y, et al. Appl Surf Sci, 2013, 279:432
14. [14] Wang Y T, Liu L P, Xiao C X, et al. Food Anal Method, 2016, 9(9):2521
15. [15] Chen L Y, Zhou T, Zhang Y P, et al. Anal Methods-UK, 2013, 5(17):4363
16. [16] Yan M.[MS Dissertation]. Beijing:Tsinghua University, 2017 闫敏.[硕士学位论文]. 北京:清华大学, 2017
17. [17] Ji X, Yu B, Su J J, et al. Polymer Materials Science & Engineering, 2019, 35(8):49 季翔, 于斌, 苏娟娟, 等. 高分子材料科学与工程, 2019, 35(8):49
18. [18] Bourlinos A B, Gournis D, Petridis D, et al. Langmuir, 2003, 19(15):6050

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磁性氧化石墨烯的制备及其在环境水样中7种内分泌干扰物检测中的应用

通讯作者: 童裳伦, E-mail:cltong@zju.edu.cn

English

Synthesis of magnetic graphene oxide modified with dodecylamine and its application for the determination of seven endocrine-disrupting chemicals in environmental water samples

Corresponding author: TONG Changlun, cltong@zju.edu.cn

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中国化学会秘书处

磁性氧化石墨烯的制备及其在环境水样中7种内分泌干扰物检测中的应用

通讯作者: 童裳伦, E-mail:cltong@zju.edu.cn

English

Synthesis of magnetic graphene oxide modified with dodecylamine and its application for the determination of seven endocrine-disrupting chemicals in environmental water samples

Corresponding author: TONG Changlun, cltong@zju.edu.cn

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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