Abstract: The organotin inorganic complexes(C₄H₉)₃Sn-O-SBA-15[Bu₃SnS]were successfully synthesized by grafting tributyltin on SBA-15 mesoporous molecular sieves in a nitrogen atmosphere. The composition,structure and properties of the samples were characterized by X-ray diffraction(XRD),transmittance electron microscopy(TEM),Hammett indicator method,N₂ adsorption-desorption,solid nuclear magnetic resonance(NMR),in-situ pyridine infrared spectroscopy(Py-IR) and so on. The results show that the hexagonal P6 mm mesostructure of parent siliceous SBA-15 is maintained in Bu₃SnS. The surface areas,proe size and volume of Bu₃SnS are all deceased with the increase of acidity,compared to those of SBA-15. Friedel-Crafts acylation of anisole and benzoyl chloride can be efficiently catalyzed in the presence of Bu₃SnS. The reaction conversion of anisole and the selectivity of p-benzoylanisole are 76.0% and 97.8%,respectively,when the molar ratio of anisole to benzoyl chloride is 0.5:1.0,the amount of catalyst is 6%,the reaction temperature is 130℃ and the reaction time is 5 h.