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微针与微流控芯片的结合应用研究进展

徐林龙 ,  金志明 ,  范一强

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引用本文: 徐林龙, 金志明, 范一强. 微针与微流控芯片的结合应用研究进展[J]. 分析化学, 2022, 50(4): 506-515. doi: 10.19756/j.issn.0253-3820.221017 shu
Citation:  XU Lin-long,  JIN Zhi-ming,  FAN Yi-qiang. Research Progress and Application of Microneedle and Microfluidics Integration[J]. Chinese Journal of Analytical Chemistry, 2022, 50(4): 506-515. doi: 10.19756/j.issn.0253-3820.221017 shu

微针与微流控芯片的结合应用研究进展

  • 北京化工大学 机电工程学院, 北京 100029

    • 通讯作者: 范一强,E-mail:fanyq@mail.buct.edu.cn
摘要: 微针因具有使用便捷、无痛等优点,在取样检测、透皮给药等生物医学诊断领域得到了日益广泛的应用。微流控芯片可对微量流体进行操控,具有试剂损耗少、检测速度快、灵敏度高等优点,在生化分析、环境科学等领域备受关注。早期,微流控芯片与微针的发展相对独立;随着微流控与微针在生物医药等领域的广泛应用和3D打印等先进微加工方法的出现,近年来微针与微流控芯片呈现出越来越多的结合应用的趋势,已初步应用于皮下取样、药物递送等方面。本文针对近年来微针与微流控芯片的结合应用进行了综述,归纳总结了微流控芯片与微针结合应用的方法体系,对二者结合应用面临的挑战进行了讨论,对其发展趋势进行了展望。

English


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  • 收稿日期:  2022-01-11
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