基于室温磷光量子点/硼酸基联吡啶盐纳米复合材料检测果糖

引用本文: 杨琪, 苗艳明, 李艳, 孙晓杰, 闫桂琴. 基于室温磷光量子点/硼酸基联吡啶盐纳米复合材料检测果糖[J]. 分析化学, 2017, 45(11): 1606-1612. doi: 10.11895/j.issn.0253-3820.170355 shu

Citation: YANG Qi, MIAO Yan-Ming, LI Yan, SUN Xiao-Jie, YAN Gui-Qin. Synthesis of Quantum Dot/Boronic Acid-substituted Bipyridinium Salt Nanohybrids as Room-temperature Phosphorescence Probe for Fructose Detection[J]. Chinese Journal of Analytical Chemistry, 2017, 45(11): 1606-1612. doi: 10.11895/j.issn.0253-3820.170355 shu

基于室温磷光量子点/硼酸基联吡啶盐纳米复合材料检测果糖

山西师范大学生命科学院, 临汾 041004
基金项目:
本文系山西省青年科技研究基金（No.201601D021109）和山西省重点化学优势学科建设项目（No.912019）资助

摘要: 以Mn掺杂的ZnS （Mn-ZnS）室温磷光（RTP）量子点的磷光为信号，以2-溴甲基苯硼酸与4，4'-联吡啶为原料合成的硼酸基联吡啶盐（BBV）为受体，带负电的量子点与带正电BBV通过静电作用形成Mn-ZnS/BBV纳米复合材料，Mn-ZnS量子点磷光猝灭，加入果糖，BBV与果糖形成阴离子硼酸酯，降低了对量子点猝灭效率，RTP恢复。考察了时间、pH值对Mn掺杂的ZnS QDs/BBV纳米复合材料磷光强度的影响，在最优条件下，此传感器检测果糖的线性范围为0.05-1.00 mmol/L，检出限为0.01 mmol/L，相关系数r为0.99。本磷光分析法简便快速、灵敏度高，有望应用于食品、医药行业中果糖含量的检测分析。

关键词:

English

Synthesis of Quantum Dot/Boronic Acid-substituted Bipyridinium Salt Nanohybrids as Room-temperature Phosphorescence Probe for Fructose Detection

College of life Science, Shanxi Normal University, Linfen 041004, China
Received Date: 05 June 2017
Revised Date: 04 September 2017

Abstract: Trace level of fructose was successfully detected by a sensor, in which the phosphorescence of Mn-doped ZnS (Mn-ZnS) room-temperature phosphorescence (RTP) quantum dots (QDs) was used as signals, and boronic acid-substituted bipyridinium salt (BBV) synthesized from 2-(bromomethyl) phenylboronic acid and 4,4'-bipyridyl was used as the receptor. The negatively-charged Mn-ZnS QDs and the positively-charged BBV electrostatically attracted each other to form Mn-ZnS QDs/BBV nanohybrids, which quenched the RTP of Mn-ZnS QDs. After addition into these nanohybrids, the fructose bonded with BBV to form an anionic borate, which largely restricted the quenching of BBV on Mn-ZnS QDs, thus the RTP was restored. In this work, we investigated the effects of pH and reaction time on the RTP of the Mn-ZnS QDs/BBV nanohybrids. Under the optimal conditions, the novel probe had a fructose detection limit of 0.01 mmol/L and a linear range of 0.05-1.0 mmol/L was achieved with correlation coefficient of 0.99. This phosphorescence sensor was superior with convenience and high speed, and can be potentially applied to the detection and analysis of fructose in foods and medicine fields.

Key words:

Quantum dots
/ Room-temperature phosphorescence
/ Boronic acid-substituted bipyridinium salt
/ Fructose

1. [1]
  Heller A, Feldman B. Chem. Rev., 2008, 108(7):2482-2505
2. [2]
  Murrey H E, Hsieh-Wilson L C. Chem. Rev., 2008, 108(5):1708-1731
3. [3]
  Nakagawa T, Hu H, Zharikov S, Tuttle K R, Short R A, Glushakova O, Ouyang X, Feig D I, Block E R, Herrera-Acosta J, Patel J M, Johnson R J. Am. J. Physiol. Renal Physiol., 2006, 290(3):F625-F631
4. [4]
  Antiochia R, Gorton L. Sens. Actuators B, 2014, 195:287-293
5. [5]
  Nishiyabu R, Kubo Y, James T D, Fossey J S. Chem. Commun., 2011, 47(4):1106-1123
6. [6]
  Shimpuku C, OzawaR, Sasaki A, Sato F, Hashimoto T, Yamauchi A, Suzuki I, Hayashita T. Chem. Commun., 2009, (13):1709-1711
7. [7]
  Wahjudi P N, Patterson M E, Lim S, Yee J K, Mao C S, Lee W N P. Clin. Biochem., 2010, 43(1):198-207
8. [8]
  Wu X, Li Z, Chen X X, Fossey J S, James T D, Jiang Y B. Chem. Soc. Rev., 2013, 42(20):8032-8048
9. [9]
  Xu S Y, Ruan Y B, Luo X X, Gao Y F, Zhao J S, Shen J S, Jiang Y B. Chem Commun., 2010, 46(32):5864-5866
10. [10]
  DENG Qi-Liang, CHEN Yang, WANG Yang, ZHANG Zhi-Jun, SU Ri-Na, LI Yan-Li, WANG Shuo. Journal of Tianjing University of Science and Technology, 2014, 29(2):71-74 邓启良, 陈洋, 王阳, 张志俊,苏日娜,李燕丽,王硕. 天津科技大学学报, 2014, 29(2):71-74
11. [11]
  Sun F, Bai T, Zhang L, Ella-Menye J-R, Liu S J, Nowinski A K, Jiang S Y, Yu Q M. Anal. Chem., 2014, 86(5):2387-2394
12. [12]
  Miao Y, Yang M, Yan G. RSC Adv., 2016, 6(11):8588-8593
13. [13]
  DU Bao-An, LIU Cheng, CAO Yu-Jiang, CHEN Li-Na. Spectroscopy and Spectral Analysis, 2014, 34(4):1070-1074 杜保安, 刘澄, 曹雨虹, 陈丽娜. 光谱学院光谱分析, 2014, 34(4):1070-1074
14. [14]
  Costa-Fernández J M, Pereiro R, Sanz-Medel A. TrAC-Trends Anal. Chem., 2006, 25(3):207-218
15. [15]
  Traviesa-Alvarez J M, Sánchez-Barragán I, Costa-Fernández J M, Pereiro R, Sanz-Medel A. Analyst, 2007, 132(3):218-223
16. [16]
  He Y, Wang H F, Yan X P. Anal. Chem., 2008, 80(10):3832-3837
17. [17]
  Wu P, Zhao T, Tian Y, Wu L, Hou X. Chem. Eur. J., 2013, 19(23):7473-7479
18. [18]
  Sharrett Z, Gamsey S, Fat J, Cunningham-Bryant D, Wessling R A, Singaram B. Tetrahedron Lett., 2007, 48(29):5125-5129
19. [19]
  Feng L, Liang F, Wang Y, Xu M, Wang X. Org. Biomol. Chem., 2011, 9(8):2938-2942
20. [20]
  Thakar R, Chen Y, Snee P T. Nano Lett., 2007, 7(11):3429-3432
21. [21]
  Chung J H, Ah C S, Jang D J. J. Phys. Chem. B, 2001, 105(19):4128-4132
22. [22]
  Sauer K, Scheer H, Sauer P. Photochem. Photobiol., 1987, 46(3):427-440
23. [23]
  Lakowicz J R, Weber G. Biochemistry, 1973, 12(21):4171-4179
24. [24]
  Suri J T, Cordes D B, Cappuccio F E, Wessling R A, Singaram B. Langmuir, 2003, 19(12):5145-5152
25. [25]
  Cordes D B, Gamsey S, Sharrett Z, Miller A, Thoniyot P, Wessling R A, Singaram B. Langmuir, 2005, 21(14):6540-6547
26. [26]
  Lorand J P, Edwards J O. J. Org. Chem., 1959, 24(6):769-774
27. [27]
  Li J, Sun Y Q, Wei Y M, Zheng J B. Chin. Chem. Lett. 2013, 24(4):291-294
28. [28]
  Cannizzo C, Amigoni-Gerbier S, Larpent C.Polymer, 2005, 46(4):1269-1276
29. [29]
  ZHU Wen-Bing, QI Li, WU Fang-Ying. Chinese Journal of Analysis Laboratory, 2012, 31(1):63-67 朱文兵, 戚丽, 吴芳英. 分析试验室, 2012, 31(1):63-67

扫一扫看文章

计量

PDF下载量: 3
文章访问数: 503
HTML全文浏览量: 50

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

基于室温磷光量子点/硼酸基联吡啶盐纳米复合材料检测果糖

English

Synthesis of Quantum Dot/Boronic Acid-substituted Bipyridinium Salt Nanohybrids as Room-temperature Phosphorescence Probe for Fructose Detection

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南：你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

计量

通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

基于室温磷光量子点/硼酸基联吡啶盐纳米复合材料检测果糖

English

Synthesis of Quantum Dot/Boronic Acid-substituted Bipyridinium Salt Nanohybrids as Room-temperature Phosphorescence Probe for Fructose Detection

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

计量

文章相关

通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

CCS Chemistry：颜徐州、鲍哲南：你的皮肤可能是一片SPMs