
Design and synthesis of cyclic acylguanidines as BACE1 inhibitors
English
Design and synthesis of cyclic acylguanidines as BACE1 inhibitors
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Key words:
- Alzheimer's disease
- / BACE1 inhibitor
- / Cyclic acylguanidine
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[10] J.N. Cumming, E.M. Smith, L.Y. Wang, et al., Structure based design of iminohydantoin BACE1 inhibitors:identification of an orally available, centrally active BACE1 inhibitor, Bioorg. Med. Chem. Lett. 22(2012) 2444-2449.[10] J.N. Cumming, E.M. Smith, L.Y. Wang, et al., Structure based design of iminohydantoin BACE1 inhibitors:identification of an orally available, centrally active BACE1 inhibitor, Bioorg. Med. Chem. Lett. 22(2012) 2444-2449.
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