Polyoxygenated dihydropyrano[2,3-<i>c</i>]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus <i>Penicillium brocae</i> MA-231 and their antimicrobial activity

Citation: Ling-Hong Meng, Xiao-Ming Li, Yang Liu, Bin-Gui Wang. Polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity[J]. Chinese Chemical Letters, 2015, 26(5): 610-612. doi: 10.1016/j.cclet.2015.01.024 shu

Polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity

通讯作者: Bin-Gui Wang,

基金项目:
Financial support from the National Natural Science Foundation of China (No. 31270403) (No. 31270403)

Technology of China (No. 2010CB833802) is gratefully acknowledged. (No. 2010CB833802)

摘要: A new polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivative, pyranonigrin F (1), together with a related known compound, pyranonigrin A (2), were isolated and identified from Penicillium brocae MA-231, an endophytic fungus obtained from the fresh tissue of the marine mangrove plant Avicennia marina. The structures of these metabolites were determined based on comprehensive spectral interpretation and the absolute configuration of compound 1 was established by X-ray crystallographic analysis. Compounds 1, and 2 showed potent activity against a broad spectrum of human-, aqua-, and plant-pathogens.

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English

Polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity

1.
a Jiangxi Key Labrotory of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang 330013, China;
2.
b College of Science, Jiangxi Agricultural University, Nanchang 330045, China

Corresponding author: Bin-Gui Wang,

Received Date: 13 November 2014
Available Online: 16 February 2015
Fund Project:

Abstract: A new polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivative, pyranonigrin F (1), together with a related known compound, pyranonigrin A (2), were isolated and identified from Penicillium brocae MA-231, an endophytic fungus obtained from the fresh tissue of the marine mangrove plant Avicennia marina. The structures of these metabolites were determined based on comprehensive spectral interpretation and the absolute configuration of compound 1 was established by X-ray crystallographic analysis. Compounds 1, and 2 showed potent activity against a broad spectrum of human-, aqua-, and plant-pathogens.

Key words:

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1.
沈阳化工大学材料科学与工程学院沈阳 110142

Polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity

通讯作者: Bin-Gui Wang,

English

Polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity

Corresponding author: Bin-Gui Wang,

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

Polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity

通讯作者: Bin-Gui Wang,

English

Polyoxygenated dihydropyrano[2,3-c]pyrrole-4,5-dione derivatives from the marine mangrove-derived endophytic fungus Penicillium brocae MA-231 and their antimicrobial activity

Corresponding author: Bin-Gui Wang,

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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