引用本文:
Mohammad Abdollahi-Alibeik, Elahe Shabani. Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by zirconium (IV) chloride as a mild and efficient catalyst[J]. Chinese Chemical Letters,
2011, 22(10): 1163-1166.
doi:
10.1016/j.cclet.2011.05.011
Citation: Mohammad Abdollahi-Alibeik, Elahe Shabani. Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by zirconium (IV) chloride as a mild and efficient catalyst[J]. Chinese Chemical Letters, 2011, 22(10): 1163-1166. doi: 10.1016/j.cclet.2011.05.011
Citation: Mohammad Abdollahi-Alibeik, Elahe Shabani. Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by zirconium (IV) chloride as a mild and efficient catalyst[J]. Chinese Chemical Letters, 2011, 22(10): 1163-1166. doi: 10.1016/j.cclet.2011.05.011
Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by zirconium (IV) chloride as a mild and efficient catalyst
摘要:
2, 3-Dihydroquinazolin-4 (1H)-ones have been synthesized in the high to excellent yields via condensation of 2-aminobenzamide with aldehydes and ketones in the presence of catalytic amount of ZrCl4 in EtOH at room temperature. Mild reaction conditions, clean reaction media, simple workup and easy purification are advantages of this methodology.
English
Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by zirconium (IV) chloride as a mild and efficient catalyst
Abstract:
2, 3-Dihydroquinazolin-4 (1H)-ones have been synthesized in the high to excellent yields via condensation of 2-aminobenzamide with aldehydes and ketones in the presence of catalytic amount of ZrCl4 in EtOH at room temperature. Mild reaction conditions, clean reaction media, simple workup and easy purification are advantages of this methodology.
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Key words:
- 2,3-Dihydroquinazolin-4(1H)-one
- / ZrCl4
- / Catalysis
- / 2-Aminobenzamide
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