Highly efficient synthesis of 2,3-dihydroquinazolin-4 (1H)-ones catalyzed by heteropoly acids in water

YingXiao Zong Yan Zhao WenCai Luo Xing Hai Yu Jun Ke Wang Yi Pan

引用本文: YingXiao Zong,  Yan Zhao,  WenCai Luo,  Xing Hai Yu,  Jun Ke Wang,  Yi Pan. Highly efficient synthesis of 2,3-dihydroquinazolin-4 (1H)-ones catalyzed by heteropoly acids in water[J]. Chinese Chemical Letters, 2010, 21(7): 778-781. doi: 10.1016/j.cclet.2010.03.022 shu
Citation:  YingXiao Zong,  Yan Zhao,  WenCai Luo,  Xing Hai Yu,  Jun Ke Wang,  Yi Pan. Highly efficient synthesis of 2,3-dihydroquinazolin-4 (1H)-ones catalyzed by heteropoly acids in water[J]. Chinese Chemical Letters, 2010, 21(7): 778-781. doi: 10.1016/j.cclet.2010.03.022 shu

Highly efficient synthesis of 2,3-dihydroquinazolin-4 (1H)-ones catalyzed by heteropoly acids in water

  • 基金项目:

    We gratefully acknowledge the financial support of Key Laboratory of Resources and Environment Chemistry of West China (No. XZ0704).

摘要: Heteropoly acids efficiently catalyzed the cyclocondensation reaction of anthranilamide with aldehydes in water at ambient temperature and afforded the corresponding 2,3-dihydro-4 (1H)-quinazolinones compounds in good to excellent yields. This method provides mild reaction conditions and clean reaction profiles, using a small quantity of catalyst and a simple workup procedure.

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  • 收稿日期:  2009-10-20
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