A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.

Wei Fu Yong Fang Lei Ya Ling Cai Dao Nian Zhou Jin Lan Ruan

引用本文: Wei Fu,  Yong Fang Lei,  Ya Ling Cai,  Dao Nian Zhou,  Jin Lan Ruan. A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.[J]. Chinese Chemical Letters, 2010, 21(7): 821-823. doi: 10.1016/j.cclet.2010.02.016 shu
Citation:  Wei Fu,  Yong Fang Lei,  Ya Ling Cai,  Dao Nian Zhou,  Jin Lan Ruan. A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.[J]. Chinese Chemical Letters, 2010, 21(7): 821-823. doi: 10.1016/j.cclet.2010.02.016 shu

A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.

  • 基金项目:

    The author is grateful to Ping Lang (Department of Analysis, Huazhong University of Science and Technology) for recording NMR spectra.

摘要: A new alkylene dihydrofuran glycoside (1) was isolated from the root bark of Morus alba L., along with moracin M-3'-O-β-D-glucopyranoside (2), and moracin M-6,3'-di-O-β-D-glucopyranoside (3). Compound 1 was identified as 2-methylene-3-methoxy-2, 5-dihydrofuran-4-O-β-D-glucopyranoside on the basis of chemical and spectroscopic data including ID and 2D NMR spectral analysis. In addition, the antioxidant activity of 1 was evaluated using the l,l-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay. The IC50 values were 2.49 and 0.45 mg/mL, respectively.

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  • 收稿日期:  2009-10-21
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