引用本文:
Yu Feng Hu, Jun Luo, Chun Xu LÜ. A mild and efficient method for nucleophilic aromatic fluorination using tetrabutylammonium fluoride as fluorinating reagent[J]. Chinese Chemical Letters,
2010, 21(2): 151-154.
doi:
10.1016/j.cclet.2009.10.014
Citation: Yu Feng Hu, Jun Luo, Chun Xu LÜ. A mild and efficient method for nucleophilic aromatic fluorination using tetrabutylammonium fluoride as fluorinating reagent[J]. Chinese Chemical Letters, 2010, 21(2): 151-154. doi: 10.1016/j.cclet.2009.10.014
Citation: Yu Feng Hu, Jun Luo, Chun Xu LÜ. A mild and efficient method for nucleophilic aromatic fluorination using tetrabutylammonium fluoride as fluorinating reagent[J]. Chinese Chemical Letters, 2010, 21(2): 151-154. doi: 10.1016/j.cclet.2009.10.014
A mild and efficient method for nucleophilic aromatic fluorination using tetrabutylammonium fluoride as fluorinating reagent
摘要:
Anhydrous tetrabutylammonium fluoride(TBAFanh.)has been found to be a highly efficient fluorinating reagent for nucleophilic aromatic fluorinations such as fluorodenitration or halogen exchange(Halex)reaction.The products were formed in high to excellent yields under surprisingly mild reaction conditions and no phenol or ether side-products were detected in these reactions.
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关键词:
- TBAFanh.
- / Fluoroaromatics
- / Fluorodenitration
- / Halex
English
A mild and efficient method for nucleophilic aromatic fluorination using tetrabutylammonium fluoride as fluorinating reagent
Abstract:
Anhydrous tetrabutylammonium fluoride(TBAFanh.)has been found to be a highly efficient fluorinating reagent for nucleophilic aromatic fluorinations such as fluorodenitration or halogen exchange(Halex)reaction.The products were formed in high to excellent yields under surprisingly mild reaction conditions and no phenol or ether side-products were detected in these reactions.
-
Key words:
- TBAFanh.
- / Fluoroaromatics
- / Fluorodenitration
- / Halex
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