引用本文:
Ganesh R. Jadhav, Mohammad U. Shaikh, Rajesh P. Kale, Charansingh H. Gill. 1-Heptanesulfonic acid sodium salt:One pot efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles[J]. Chinese Chemical Letters,
2009, 20(5): 535-538.
doi:
10.1016/j.cclet.2008.12.004
Citation: Ganesh R. Jadhav, Mohammad U. Shaikh, Rajesh P. Kale, Charansingh H. Gill. 1-Heptanesulfonic acid sodium salt:One pot efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles[J]. Chinese Chemical Letters, 2009, 20(5): 535-538. doi: 10.1016/j.cclet.2008.12.004
Citation: Ganesh R. Jadhav, Mohammad U. Shaikh, Rajesh P. Kale, Charansingh H. Gill. 1-Heptanesulfonic acid sodium salt:One pot efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles[J]. Chinese Chemical Letters, 2009, 20(5): 535-538. doi: 10.1016/j.cclet.2008.12.004
1-Heptanesulfonic acid sodium salt:One pot efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles
摘要:
Synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles by the reaction of o-phenylenediamine with substituted aromatic aldehydes in the presence of 1-heptanesulfonic acid sodium salt (10 mol%) at room temperature. The reactions were performed in acetonitrile:water (8:2). The method was proved to be eco-friendly, convenient and the products were isolated with good yields (82-90%).
English
1-Heptanesulfonic acid sodium salt:One pot efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles
Abstract:
Synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles by the reaction of o-phenylenediamine with substituted aromatic aldehydes in the presence of 1-heptanesulfonic acid sodium salt (10 mol%) at room temperature. The reactions were performed in acetonitrile:water (8:2). The method was proved to be eco-friendly, convenient and the products were isolated with good yields (82-90%).
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Key words:
- 1-Heptanesulfonic acid sodium salt
- / Water
- / Aryl aldehyde
- / Benzimidazole
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