Solvent- and catalyst-free synthesis of dihydropyrimidinthiones in one-pot under focused microwave irradiation conditions

Hong Wen Zhan Jin Xian Wang Xi Tian Wang

引用本文: Hong Wen Zhan,  Jin Xian Wang,  Xi Tian Wang. Solvent- and catalyst-free synthesis of dihydropyrimidinthiones in one-pot under focused microwave irradiation conditions[J]. Chinese Chemical Letters, 2008, 19(10): 1183-1185. doi: 10.1016/j.cclet.2008.06.039 shu
Citation:  Hong Wen Zhan,  Jin Xian Wang,  Xi Tian Wang. Solvent- and catalyst-free synthesis of dihydropyrimidinthiones in one-pot under focused microwave irradiation conditions[J]. Chinese Chemical Letters, 2008, 19(10): 1183-1185. doi: 10.1016/j.cclet.2008.06.039 shu

Solvent- and catalyst-free synthesis of dihydropyrimidinthiones in one-pot under focused microwave irradiation conditions

  • 基金项目:

    The work was supported by the Natural Science Foundation of China (No. 20272047, 20572086), the Natural Science Foundation of Gansu Province (No. 3ZS051-A25-001) and Key Laboratory of Eco-Environment-Related Polymer Material (Northwest Normal University), Ministry of Education of China.

摘要: Fifteen dihydropyrimidinthiones have been synthesized by microwave-assisted Biginelli reactions without any solvent of catalyst.The advantages of this novel protocol include the excellent yield,operational simplicity,short time and the avoidance of the use of organic solvents and catalysts.

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  • 收稿日期:  2008-04-07
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