引用本文:
Yu Cai He, Jian He Xu, Yi Xu, Li Ming Ouyang, Jiang Pan. Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401[J]. Chinese Chemical Letters,
2007, 18(6): 677-680.
doi:
10.1016/j.cclet.2007.04.034
Citation: Yu Cai He, Jian He Xu, Yi Xu, Li Ming Ouyang, Jiang Pan. Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401[J]. Chinese Chemical Letters, 2007, 18(6): 677-680. doi: 10.1016/j.cclet.2007.04.034
Citation: Yu Cai He, Jian He Xu, Yi Xu, Li Ming Ouyang, Jiang Pan. Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401[J]. Chinese Chemical Letters, 2007, 18(6): 677-680. doi: 10.1016/j.cclet.2007.04.034
Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401
摘要:
By using acetonitrile as the sole nitrogen source, a microbial strain with high nitrilase activity, named as Alcaligenes sp.ECU0401, was newly isolated from soil, which could enantioselectively transform racemic mandelonitrile into (R)-(-)-mandelic acid, with an enantiomeric excess of >99.9%.
English
Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401
Abstract:
By using acetonitrile as the sole nitrogen source, a microbial strain with high nitrilase activity, named as Alcaligenes sp.ECU0401, was newly isolated from soil, which could enantioselectively transform racemic mandelonitrile into (R)-(-)-mandelic acid, with an enantiomeric excess of >99.9%.
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Key words:
- Mandelonitrile
- / Nitrilase
- / (R)-(-)-Mandelic acid
- / Screening
- / Alcaligenes sp. ECU0401
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