Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes

Citation: Tian Sun, Yu-feng Zhang, Chun-lin Chen, Xiang-zhuang Gong, Jian-qiang Meng. Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes[J]. Chinese Journal of Polymer Science, 2014, 32(7): 880-891. doi: 10.1007/s10118-014-1462-5 shu

Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes

1.
State Key Laboratory of Hollow Fiber Membrane Material and Membrane Process, Tianjin Polytechnic University, Tianjin 300387, China
基金项目:
This work was financially supported by the National Natural Science Foundation of China (No. 21274108) and the National High Technology Research and Development Program of China (No. 2012AA03A602). Prof. Jian-qiang Meng thanks Prof. Zi-Chen Li and Mr. Lei Li (Peking University) for BET measurements.

摘要: Surface-initiated atom transfer radical polymerization (SI-ATRP) was used to tether poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) onto microporous PVDF membranes in order to synthesize membrane adsorbers for protein adsorption. The alkaline treatment and bromine addition reaction were used to anchor ATRP initiators on membrane surface. Then PDMAEMA was grafted from the membrane surface via SI-ATRP. Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) revealed the chemical composition and surface topography of the PVDF-g-PDMAEMA membrane surfaces. These results showed that PDMAEMA was grafted from the membrane surface successfully and a grafting yield as high as 1500 mg/cm2 was achieved. The effects of the grafting time and the density of initiators on the static and dynamic binding capacity of bovine serum albumin (BSA) were systematically investigated. Both the static and dynamic binding capacities increase with the bromination and polymerization time. However, the benefits of the initiator density on binding capacities are limited by the graft density of PDMAEMA chains.

关键词:

English

Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes

1.
State Key Laboratory of Hollow Fiber Membrane Material and Membrane Process, Tianjin Polytechnic University, Tianjin 300387, China
Received Date: 09 October 2013
Revised Date: 31 December 2013
Available Online: 05 July 2014
Fund Project:
This work was financially supported by the National Natural Science Foundation of China (No. 21274108) and the National High Technology Research and Development Program of China (No. 2012AA03A602). Prof. Jian-qiang Meng thanks Prof. Zi-Chen Li and Mr. Lei Li (Peking University) for BET measurements.

Abstract: Surface-initiated atom transfer radical polymerization (SI-ATRP) was used to tether poly(2-dimethylaminoethyl methacrylate) (PDMAEMA) onto microporous PVDF membranes in order to synthesize membrane adsorbers for protein adsorption. The alkaline treatment and bromine addition reaction were used to anchor ATRP initiators on membrane surface. Then PDMAEMA was grafted from the membrane surface via SI-ATRP. Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) revealed the chemical composition and surface topography of the PVDF-g-PDMAEMA membrane surfaces. These results showed that PDMAEMA was grafted from the membrane surface successfully and a grafting yield as high as 1500 mg/cm2 was achieved. The effects of the grafting time and the density of initiators on the static and dynamic binding capacity of bovine serum albumin (BSA) were systematically investigated. Both the static and dynamic binding capacities increase with the bromination and polymerization time. However, the benefits of the initiator density on binding capacities are limited by the graft density of PDMAEMA chains.

Key words:

1. [1]
  Walsh. G., Nat., Biotechnol., 2006, 24: 769
2. [2]
  Bhut, B.V., Wickramamsinghe, S.R. and Husson, S.M., J. Membr. Sci., 2008, 325: 176
3. [3]
  Saxena, A., Tripathi, B.P., Kumar, M. and Shahi, V.K., Colloid Interface. Sci., 2009, 145: 1
4. [4]
  Zhou, D., Too, C.O., Wallace, G.G., Hodges, A.M. and Mau, A.W.H., React. Funct. Polym., 2000, 45: 217
5. [5]
  Lightfoot, E.N. and Moscariello, J.S., Biotechnol. Bioeng., 2004, 87: 257
6. [6]
  Ghosh, R., Handbook of membrane separations, CRC press, 2008, p. 497
7. [7]
  Zeng, X.Z. and Ruckenstein, E., Biotechnol. Prog., 1999, 15: 1003
8. [8]
  Charcosset, C., J. Chem. Technol. Biotechnol., 1998, 71: 95
9. [9]
  Roper, D.K. and Lightfoot, E.N., J. Chromatogr. A., 1995, 702: 3
10. [10]
  Ghosh, R., J. Chromatogr. A., 2002, 952: 13
11. [11]
  Liu, Y.Z., Feng, Z.C., Shao, Z.Z. and Chen, X., Mater. Sci. Eng., C., 2012, 32: 1669
12. [12]
  Wickramasinghe, S.R., Carlson, J.O., Teske, C., Hubbuch, J. and Ulbricht, M., J. Membr. Sci., 2006, 281: 609
13. [13]
  Ghosh, R. and Wong, T., J. Membr. Sci., 2006, 281: 532
14. [14]
  Avramescu, M.E., Borneman, Z. and Wessling, M., Biotechnol. Bioeng., 2003, 84: 564
15. [15]
  Klein, E., J. Membr. Sci., 2000, 179: 1
16. [16]
  Haider, S. and Park, S.Y., J. Membr. Sci., 2009, 328: 90
17. [17]
  Saeed, K., Haider, S., Oh, T.J. and Park, S.Y., J. Membr. Sci., 2008, 322: 400
18. [18]
  Che, A.F., Huang, X.J. and Xu, Z.K., J. Membr. Sci., 2011, 366: 272
19. [19]
  Ulbricht, M. and Yang, H., Chem. Mater., 2005, 17: 2622
20. [20]
  Kacar, Y. and Arica, M.Y., Colloids. Surf. B., 2001, 22: 227
21. [21]
  Yusof, A.H.M. and Ulbrict, M., Desalination, 2006, 200: 462
22. [22]
  Hagiwara, K., Yonedu, S., Saito, K., Shiraishi, T., Sugo, T., Tojyo, T. and Katayama, E., J. Chromatogr. B, 2005, 821: 153
23. [23]
  Kobayashi, K., Tsuneda, S., Saito, K., Yamagishi, H., Furusaki, S. and Sugo, T.V., J. Membr. Sci., 1993, 76: 209
24. [24]
  Kumar, V., Bhardwaj, Y.K., Jamdar, S.N., Goel, N.K. and Sabharwal, S., J. Appl. Polym. Sci., 2006, 102: 5512
25. [25]
  Inoue, Y., Nakanishi, T. and Ishihara, K., React. Funct. Polym., 2011, 71: 350
26. [26]
  Samanta, S., Layek, R.K. and Nandi, A.K., React. Funct. Polym., 2011, 71: 1045
27. [27]
  Singh, N., Husson, S.M., Zdyrko, B. and Luzinov, I., J. Membr. Sci., 2005, 262: 81
28. [28]
  Singh, N., Wang, J., Ulbricht, M., Wickramasinghe, S.R. and Husson, S.M., J. Membr. Sci., 2008, 309: 64
29. [29]
  Zeng, R., Chen, Y.W., Zhou, W.H., Xiao, S.Q., Xiao, J.C. and Song, C.S., J. Mater. Sci., 2010, 45: 1610
30. [30]
  Zeng, R.,Chen, Y.W.,Zhou, W.H.,Xiao, S.Q.,Xiao, J.C. andSong, C.S., J. Mater. Sci., 2010, 45: 1610
31. [31]
  Singh, N.,Chen, Z.,Tomer, N.,Wickramasinghe, S.R.,Soice, N. andHusson, S.M., J. Membr. Sci., 2008, 311: 225
32. [32]
  Singh, N., Chen, Z., Tomer, N., Wickramasinghe, S.R., Soice, N. and Husson, S.M., J. Membr. Sci., 2008, 311: 225
33. [33]
  Sun,Y., Gao, X.L., Wang, Z.N. and Gao, C.J., J. Membr. Sci., 2012, 394―395: 107
34. [34]
  S,Y.,Gao, X.L., Wang, Z.N. andGao, C.J., J. Membr. Sci., 2012, 394-395: 107
35. [35]
  Bhut, B.V. and Husson, S.M., J. Membr. Sci., 2009, 337: 215
36. [36]
  Bhut, B.V. andHusson, S.M., J. Membr. Sci., 2009, 337: 215
37. [37]
  Zhao, Y.Z., Yang, X.L. and Huang, W.Q., Chinese J. Polym. Sci., 2005, 23(3): 235
38. [38]
  Zhao, Y.Z., Yang, X.L. and Huang, W.Q., Chinese J. Polym. Sci., 2005, 23(3): 235
39. [39]
  Davis, K.A. and Matyjaszewski, K., Chinese J. Polym. Sci., 2004, 22(2): 195
40. [40]
  Davis, K.A. and Matyjaszewski, K., Chinese J. Polym. Sci., 2004, 22(2): 195
41. [41]
  Liu, F.,Hashim, N.A.,Liu,Y.T.,Abed, M.R. andMoghareh, K. Li., J. Membr. Sci., 2011, 375: 1
42. [42]
  Liu, F., Hashim, N.A., Liu, Y.T., Abed, M.R. and Moghareh, K. Li., J. Membr. Sci., 2011, 375: 1
43. [43]
  Oh, B.S.,Jang, H.Y.,Cho, J., Lee, S., Lee, L.E., Kim, I.S.,Hwang, T.M. andKang, J.W.,Desalination, 2009, 238: 90
44. [44]
  Oh, B.S., Jang, H.Y., Cho, J., Lee, S., Lee, L.E., Kim, I.S., Hwang, T.M. and Kang, J.W., Desalination, 2009, 238: 90
45. [45]
  Sun, Y.Y., Liu, Y.Q., Zhao, G.Z., Zhou, X., Gao, J.G. and Zhang, Q.J., J. Mater. Sci., 2008, 43: 4625
46. [46]
  Sun, Y.Y.,Liu, Y.Q.,Zhao, G.Z., Zhou, X.,Gao, J.G. andZhang, Q.J., J. Mater. Sci., 2008, 43: 4625
47. [47]
  Zhang, N.Y.,Liu, M.Z.,Shen, Y.G.,Chen, J.,Dai, L.L. andGao, C.M., J. Mater. Sci., 2011, 46: 1523
48. [48]
  Zhang, N.Y., Liu, M.Z., Shen, Y.G., Chen, J., Dai, L.L. and Gao, C.M., J. Mater. Sci., 2011, 46: 1523
49. [49]
  Kusumo, A.,Bombalski, L.,Lin, Q.,Matyjaszewski, K.,Scheneider, J.W. andTilton, R.D.,Langmuir, 2007, 23: 4448
50. [50]
  Kusumo, A., Bombalski, L., Lin, Q., Matyjaszewski, K., Scheneider, J.W. and Tilton, R.D., Langmuir, 2007, 23: 4448
51. [51]
  Meng, J.Q., Chen, C.L., Huang, L.P., Du, Q.Y. and Zhang, Y.F., Appl. Surf. Sci., 2011, 257: 6282
52. [52]
  Meng, J.Q., Chen, C.L.,Huang,L.P.,Du, Q.Y. andZhang, Y.F., Appl. Surf. Sci., 2011, 257: 6282
53. [53]
  Alchikh, M., Fond, C., Frre, Y. and Pelletier, H., J. Mater. Sci., 2010, 45: 2311
54. [54]
  Alchikh, M.,Fond, C.,Frre, Y. andPelletier, H., J. Mater. Sci., 2010, 45: 2311
55. [55]
  Ross, G.J.,Watts, J.F.,Hill, M.P. andMorrissey, P.,Polymer, 2000, 41: 1685
56. [56]
  Ross, G.J., Watts, J.F., Hill, M.P. and Morrissey, P., Polymer, 2000, 41: 1685
57. [57]
  Ross, G.J., Watts, J.F., Hill, M.P. and Morrissey, P., Polymer, 2001, 42: 403
58. [58]
  Ross, G.J., Watts, J.F., Hill, M.P. and Morrissey, P., Polymer, 2001, 42: 403
59. [59]
  Bottino, A., Capannelli, G. and Comite, A., J. Membr. Sci., 2006, 273: 20
60. [60]
  Bottino, A.,Capannelli, G. andComite, A.,J.Membr. Sci., 2006, 273: 20
61. [61]
  Bottino, A.,Capannelli, G.,Monticelli, O. andPiaggio, P., J. Membr. Sci., 2000, 166: 23
62. [62]
  Bottino, A., Capannelli, G., Monticelli, O. and Piaggio, P., J. Membr. Sci., 2000, 166: 23
63. [63]
  Marchand-Brynaert, J.,Jongen, N. andDewez, J.L.,J. Polym. Sci, Part. A: Polym. Chem., 1997, 35: 1227
64. [64]
  Marchand-Brynaert, J., Jongen, N. and Dewez, J.L., J. Polym. Sci. Part A: Polym. Chem., 1997, 35: 1227
65. [65]
  Han, M.J., Baroa, G.N.B. and Jung, B., Desalination, 2011, 270: 76
66. [66]
  Han, M.J.,Baroa, G.N.B. andJung, B.,Desalination, 2011, 270: 76
67. [67]
  Chang, Y., Ko, C.Y., Shih, Y.J., Qumener, D., Deratan, A., Wei, T.C., Wang, D.M. and Lai, J.Y., J. Membr. Sci., 2009, 345: 160
68. [68]
  Chang, Y.,Ko, C.Y.,Shih, Y.J.,Qumener, D.,Deratan, A.,Wei, T.C.,Wang, D.M. andLai, J.Y., J. Membr. Sci., 2009, 345: 160
69. [69]
  Zhai, G. Q., Shi, Z. L.,Kang, E. T. andNeoh, K. G.,Biomacromolecules, 2005, 5: 974
70. [70]
  Zhai, G.Q., Shi, Z.L., Kang, E.T. and Neoh, K.G., Biomacromolecules, 2005, 5: 974
71. [71]
  Tomickia, F., Krix, D., Nienhaus, H. and Ulbricht, M., J. Membr. Sci., 2011, 377: 124
72. [72]
  Tomickia, F.,Krix, D.,Nienhaus, H. andUlbricht, M., J. Membr. Sci., 2011, 377: 124
73. [73]
  Liu, Y., Kelp, V., Zdyrko, B. and Luzinov, I., Langmuir, 2004, 20: 6710
74. [74]
  Liu, Y.,Kelp, V.,Zdyrko, B. andLuzinov, I.,Langmuir, 2004, 20: 6710
75. [75]
  Li, P.F., Xie, R., Jiang, J.C., Meng, T., Yang, M., Ju, X.J., Yang, L.H. and Chu, L.Y., J. Membr. Sci., 2009, 337: 3109: 64
76. [76]
  Li, P.F.,Xie, R.,Jiang, J.C.,Meng, T.,Yang, M.,Ju, X.J.,Yang, L.H. andChu, L.Y., J. Membr. Sci., 2009, 337: 310

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沈阳化工大学材料科学与工程学院沈阳 110142

Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes

English

Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes

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中国化学会秘书处

Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes

English

Synthesis of Membrane Adsorbers via Surface Initiated ATRP of 2-Dimethylaminoethyl Methacrylate from Microporous PVDF Membranes

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CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

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