引用本文:
Chun Yan XU, Ming Zhi HUANG. An Approach to New Water-soluble Oligo(ethylene glycol) Camptothecin Analogues by 1,3-Dipolar Cycloaddition[J]. Chinese Chemical Letters,
2006, 17(7): 883-886.
Citation: Chun Yan XU, Ming Zhi HUANG. An Approach to New Water-soluble Oligo(ethylene glycol) Camptothecin Analogues by 1,3-Dipolar Cycloaddition[J]. Chinese Chemical Letters, 2006, 17(7): 883-886.
Citation: Chun Yan XU, Ming Zhi HUANG. An Approach to New Water-soluble Oligo(ethylene glycol) Camptothecin Analogues by 1,3-Dipolar Cycloaddition[J]. Chinese Chemical Letters, 2006, 17(7): 883-886.
An Approach to New Water-soluble Oligo(ethylene glycol) Camptothecin Analogues by 1,3-Dipolar Cycloaddition
摘要:
Combined with an effective copper-catalyzed triazole-forming reaction, a series of novel camptothecin derivatives were synthesized. Incorporating oligo(ethylene glycol) chains into the derivatives enhanced their water-solubility when compared to the parent compound (up to 55-fold).
English
An Approach to New Water-soluble Oligo(ethylene glycol) Camptothecin Analogues by 1,3-Dipolar Cycloaddition
Abstract:
Combined with an effective copper-catalyzed triazole-forming reaction, a series of novel camptothecin derivatives were synthesized. Incorporating oligo(ethylene glycol) chains into the derivatives enhanced their water-solubility when compared to the parent compound (up to 55-fold).
-
Key words:
- Click chemistry
- / 20(S)-camptothecin
- / water-soluble derivatives
扫一扫看文章
计量
- PDF下载量: 0
- 文章访问数: 0
- HTML全文浏览量: 0
下载:
