Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor

引用本文: Zhan Zhu LIU, Shi Zhi CHEN. Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor[J]. Chinese Chemical Letters, 2003, 14(11): 1127-1129. shu

Citation: Zhan Zhu LIU, Shi Zhi CHEN. Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor[J]. Chinese Chemical Letters, 2003, 14(11): 1127-1129. shu

Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor

Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050

摘要: A mild two-step method was used to cleave the lactam ring of the tricyclic intermediate 1. A key racemic amino alcohol precursor 5 for the construction of Et-743 skeleton was synthesized from 1 through four steps in total yield of 47%.

关键词:

Et-743
/ lactam
/ cleavage

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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor

English

Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor

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通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor

English

Synthetic Studies of Et-743, Preparation of A Racemic Amino Alcohol Precursor

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

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通讯作者: 陈斌, bchen63@163.com

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