An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes

Yu Li XIE Qin ZHU Xing Rong QIN Yu Yuan XIE

引用本文: Yu Li XIE,  Qin ZHU,  Xing Rong QIN,  Yu Yuan XIE. An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes[J]. Chinese Chemical Letters, 2003, 14(1): 25-28. shu
Citation:  Yu Li XIE,  Qin ZHU,  Xing Rong QIN,  Yu Yuan XIE. An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes[J]. Chinese Chemical Letters, 2003, 14(1): 25-28. shu

An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes

摘要: A simple and efficient procedure for synthesis of 1-hydroxymcthylene-1,1-bisphosphoates from aldehydes is deseribed. This method was applied to the synthesis of nowel catcchol substituted bisphosphonatcs as the anti-ostcoporosis agents.

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  • 收稿日期:  2002-04-01
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