引用本文:
Jian Zhong WU, Lei WANG, Guang YANG, Tian Xian ZENG, Liang Nian JI. RUTHENIUM COORDINATION COMPOUNDS WITH POLYPYRIDINES V.DNA-BINDING STUDIES OF Ru(Ⅱ) COORDINATION COMPOUNDS WITH (2-PHENYL-) IMIDAZO [f] 1,10-PHENANTHROLINE[J]. Chinese Chemical Letters,
1995, 6(11): 999-1002.
Citation: Jian Zhong WU, Lei WANG, Guang YANG, Tian Xian ZENG, Liang Nian JI. RUTHENIUM COORDINATION COMPOUNDS WITH POLYPYRIDINES V.DNA-BINDING STUDIES OF Ru(Ⅱ) COORDINATION COMPOUNDS WITH (2-PHENYL-) IMIDAZO [f] 1,10-PHENANTHROLINE[J]. Chinese Chemical Letters, 1995, 6(11): 999-1002.
Citation: Jian Zhong WU, Lei WANG, Guang YANG, Tian Xian ZENG, Liang Nian JI. RUTHENIUM COORDINATION COMPOUNDS WITH POLYPYRIDINES V.DNA-BINDING STUDIES OF Ru(Ⅱ) COORDINATION COMPOUNDS WITH (2-PHENYL-) IMIDAZO [f] 1,10-PHENANTHROLINE[J]. Chinese Chemical Letters, 1995, 6(11): 999-1002.
RUTHENIUM COORDINATION COMPOUNDS WITH POLYPYRIDINES V.DNA-BINDING STUDIES OF Ru(Ⅱ) COORDINATION COMPOUNDS WITH (2-PHENYL-) IMIDAZO [f] 1,10-PHENANTHROLINE
摘要:
The binding of [Ru(bpy)2(IP)]2+(b2IP), [Ru(bpy)2(PIP)]2+(b2PIP),[Ru(phen)2(IP)]2+(p2IP), [Ru(phen)2(PIP)]2+(p2PIP) to calf thymus DNA was investigated using electronic absorption,circular dichroism and fluorescence emission spectroscopies.CD spectra of dialyzates indicate enantioselectivity associated with binding.Evidence of intercalative binding is also provided by hypochromicity in the MLCT bands,increased emission intensities and curvature of emission quenching by [Fe(CN)8]4-.The total binding affinities seem to be in the order b2IP < b2PIP ≤ P2IP < P2PIP,which is consistent with the order of ligand planarity,extent of aromatic π-system and hydrophobicity,bpy << phen < IP < PIP.
English
RUTHENIUM COORDINATION COMPOUNDS WITH POLYPYRIDINES V.DNA-BINDING STUDIES OF Ru(Ⅱ) COORDINATION COMPOUNDS WITH (2-PHENYL-) IMIDAZO [f] 1,10-PHENANTHROLINE
Abstract:
The binding of [Ru(bpy)2(IP)]2+(b2IP), [Ru(bpy)2(PIP)]2+(b2PIP),[Ru(phen)2(IP)]2+(p2IP), [Ru(phen)2(PIP)]2+(p2PIP) to calf thymus DNA was investigated using electronic absorption,circular dichroism and fluorescence emission spectroscopies.CD spectra of dialyzates indicate enantioselectivity associated with binding.Evidence of intercalative binding is also provided by hypochromicity in the MLCT bands,increased emission intensities and curvature of emission quenching by [Fe(CN)8]4-.The total binding affinities seem to be in the order b2IP < b2PIP ≤ P2IP < P2PIP,which is consistent with the order of ligand planarity,extent of aromatic π-system and hydrophobicity,bpy << phen < IP < PIP.
扫一扫看文章
计量
- PDF下载量: 0
- 文章访问数: 0
- HTML全文浏览量: 0
下载:
