2025 Volume 40 Issue 5

2025, 40(5):
[Abstract](4) [FullText HTML] [PDF 13903KB](1)
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Suggestions on Theoretical and Experimental Teaching Contents of Applied Chemistry Majors in Universities
Shuyong Zhang , Zhong Wei , Gang Ni , Chunyan Sun , Jianping Li , Hualong Xu , Xijiang Han , Qiue Cao , Yanguang Wang , Yi Yang , Yuqiang Ding , Wenqing Zhang
2025, 40(5): 1-8  doi: 10.12461/PKU.DXHX202404002
[Abstract](8) [FullText HTML] [PDF 443KB](0)
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That the current theoretical and experimental teaching contents of applied chemistry major is similar to that of chemistry major does not meet the needs of the training of applied talents. In this paper, the historical development of the suggestions on the teaching contents of applied chemistry major was summarized. On analyzing the needs of professional certification standards and the development of professional characteristics, the suggestions on the theoretical and experimental teaching contents of applied chemistry major are put forward. Some suggestions on the curriculum system and practical teaching of applied chemistry are also presented. It is of reference significance for the applied chemistry majors to better cultivate the applied and applied research talents.
Suggestions on Construction and Evaluation Standards for First-Class Chemical Experiment Teaching
Shuyong Zhang , Wenfeng Jiang , Changsheng Lu , Genrong Qiang , Yongmei Liu , Xiangyang Tang , Dongcheng Liu , Lili Zhang
2025, 40(5): 9-14  doi: 10.12461/PKU.DXHX202502114
[Abstract](6) [FullText HTML] [PDF 369KB](1)
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In order to promote the construction of the first-class course of chemical experiment and improve the construction level and teaching effectiveness of the experimental teaching, the virtual teaching and research office of the Reform Research of Chemical Experiment Teaching of the Ministry of Education decided to give suggestions on standards for the construction and evaluation of the first-class course of chemical experiment teaching. The standard suggestions which mainly concerns teaching concept, contents, resources, methods and means, evaluation and characteristic construction have certain guiding significance for promoting the reform and construction of experimental teaching.
Suggestions on Teaching Contents and Requirements of Chemistry Laboratory Safety for Chemistry Majors in Higher Education
Ling Yang , Yupeng Guo , Jingcheng Ji , Xiangjuan Qi , Chuanli Qin , Pingping Zhu , Shuyong Zhang
2025, 40(5): 15-22  doi: 10.12461/PKU.DXHX202412103
[Abstract](5) [FullText HTML] [PDF 428KB](0)
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Laboratory safety is the basic content of chemical professional knowledge system. The suggestions clarify teaching objectives of laboratory safety course for chemistry majors. Specific teaching content and teaching requirements including knowledge, ability and quality that should be achieved are suggested. Colleges and universities can refer to the suggestions to further optimize chemical laboratory safety teaching, and consolidate laboratory safety foundation for experimental teaching and scientific research.
Suggestions on Teaching Contents and Requirements of Inorganic Chemistry Experiment for Chemistry Majors in Higher Education
Wenwei Zhang , Yanping Ren , Weihong Li , Xiaohang Qiu , Mei Shi , Yuwen Liu , Zhilin Wang
2025, 40(5): 23-31  doi: 10.12461/PKU.DXHX202405120
[Abstract](7) [FullText HTML] [PDF 463KB](0)
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This proposal aims to comprehensively implement the National Teaching Standards for Chemistry Majors and the guidelines from the Ministry of Education’s Instructional Committee for Higher Chemistry Education. It focuses on enhancing the quality of inorganic chemistry experimental teaching, and promoting reform and construction in this area. The suggestions include clear teaching objectives, recommended experimental contents, and specific teaching requirements to achieve targeted knowledge, skills, and competencies. Universities are encouraged to use these recommendations to optimize their inorganic chemistry experimental teaching and elevate the overall quality of experimental education.
The Use of pH Indicator Papers and pH Meters
Faqiong Zhao , Xiaohang Qiu , Yanping Ren , Juanjuan Song , Dongcheng Liu , Xiuqiong Zeng , Wenwei Zhang , Mei Shi , Min Hu , Wan Li , Yongxian Fan , Yiru Wang , Xiuyun Wang , Weihong Li , Yong Fan , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 32-39  doi: 10.12461/PKU.DXHX202503099
[Abstract](6) [FullText HTML] [PDF 1372KB](0)
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During the process of chemical synthesis and analytical determination, the pH of the solution is one of the important factors affecting the experimental results. Mastering the method of measuring the pH of a solution proficiently is a basic experimental skill that students majoring in chemistry in colleges and universities must possess. This paper introduces the types, working principles, and usage methods of pH test papers and pH meters, and puts forward standardized suggestions for the specific operations during the measurement process.
Basic Operations and Standardization Suggestions for Organic Chemistry Distillation Experiments
Houjin Li , Shuanglian Cai , Yuan Zheng , Zhanxiang Liu , Chengshan Yuan , Lin Wu , Guangao Yu , Jie Han , Qingwen Liu , Xin Du , Ying Xiong , Qihan Zhang , Xingwen Sun , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 40-54  doi: 10.12461/PKU.DXHX202411053
[Abstract](4) [FullText HTML] [PDF 1674KB](1)
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This paper analyzes and compares the commonalities and specific characteristics of various distillation techniques, including normal pressure distillation, air-condensation distillation, distillation of flammable and explosive low-boiling organics, reduced pressure distillation, fractional distillation, steam distillation, and rotary evaporation. The scope and conditions for applying each experimental operation are clarified, and detailed standard operating recommendations are provided for each type of distillation. Additionally, common non-standard or incorrect practices are highlighted. These standardization suggestions are scientific, reasonable, and highly applicable, contributing to improved experimental efficiency, success rates, and overall safety.
Recommendations for Basic Operations and Standards for Organic Chemical Extraction and Washing Experiments
Zhanxiang Liu , Chengshan Yuan , Jie Han , Shuanglian Cai , Qihan Zhang , Lin Wu , Yuan Zheng , Xingwen Sun , Qingwen Liu , Ying Xiong , Guangao Yu , Xin Du , Houjin Li , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 55-65  doi: 10.12461/PKU.DXHX202410039
[Abstract](5) [FullText HTML] [PDF 1821KB](0)
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Extraction, washing, and drying are fundamental components of organic chemistry laboratory. Proficiently mastering and applying extraction and washing techniques to separate and purify organic compounds is an essential experimental skill that chemistry undergraduates must acquire. Due to the lack of unified and clear operating standards, actual teaching and experimental processes may lead to deviations in results, reagent waste, and even safety incidents. This article provides basic operational guidelines and standard recommendations for extraction, washing, and subsequent drying experiments in organic chemistry, aiming to serve as a reference for domestic colleagues engaged in laboratory teaching and scientific research.
Basic Operations and Specification Suggestions for Organic Chemical Recrystallization Experiments
Xuewei Qian , Xingwen Sun , Houjin Li , Zhanxiang Liu , Yuan Zheng , Lin Wu , Shuanglian Cai , Ying Xiong , Guangao Yu , Qingwen Liu , Jie Han , Xin Du , Chengshan Yuan , Qihan Zhang , Shuyong Zhang , Jianrong Zhang
2025, 40(5): 66-75  doi: 10.12461/PKU.DXHX202503126
[Abstract](5) [FullText HTML] [PDF 1517KB](0)
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This article conducts a comprehensive and in-depth introduction of the basic recrystallization operations commonly used in organic chemistry experiments, covering the principles of recrystallization, solvent selection, basic operation steps, and precautions. Through theoretical explanations and analysis of actual cases, the influence of various factors on the recrystallization effect is discussed in detail, aiming to provide a set of systematic, scientific and practical recrystallization operation standard guidelines for organic chemistry experiments, so as to achieve efficient and high-quality purification of organic compounds.
Standardized Operational Guidelines for Sublimation in Organic Chemistry Experiments
Chengshan Yuan , Zhanxiang Liu , Xin Du , Jie Han , Yuan Zheng , Ying Xiong , Qingwen Liu , Guangao Yu , Lin Wu , Shuanglian Cai , Xingwen Sun , Qihan Zhang , Houjin Li , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 76-83  doi: 10.12461/PKU.DXHX202504015
[Abstract](3) [FullText HTML] [PDF 846KB](0)
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Sublimation is an important technique for the separation and purification of solid substances, widely used in the refinement of natural products and synthetic compounds. Due to differences in experimental content, conditions, and procedural descriptions in textbooks, experimenters often encounter non-standardized operations during sublimation experiments, leading to insufficient product purity, reduced yields, significant deviations in experimental results, and even safety hazards. Based on experience in organic chemistry laboratory teaching and scientific research practice, this paper systematically analyzes the applicable scope and key operational points of both atmospheric and vacuum sublimation. Furthermore, standardized operational recommendations are proposed to ensure the safety, efficiency, and reproducibility of experiments, providing a valuable reference for researchers in the field.
Basic Operations and Standardization Suggestions for Organic Chemistry Reflux Experiments
Yuan Zheng , Houjin Li , Zhanxiang Liu , Lin Wu , Shuanglian Cai , Ying Xiong , Guangao Yu , Xingwen Sun , Qingwen Liu , Jie Han , Xin Du , Chengshan Yuan , Qihan Zhang , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 84-92  doi: 10.12461/PKU.DXHX202411045
[Abstract](5) [FullText HTML] [PDF 2169KB](0)
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Reflux is a fundamental technique in organic chemistry laboratory. Most organic chemical reactions and operations, such as recrystallization, are conducted under reflux conditions. Mastery of reflux operations is a crucial experimental skill that chemistry students must acquire. In organic chemistry experiments, improper reflux operations can lead to low yields, experimental failures, and even safety incidents. This article provides standard operating suggestions for various reflux operations in organic chemistry laboratory, with the aim of offering guidance for colleagues in China who are engaged in laboratory teaching and scientific research.
Basic Operations and Specification Suggestions for Organic Chemical Chromatography Experiments
Houjin Li , Lin Wu , Xingwen Sun , Yuan Zheng , Zhanxiang Liu , Shuanglian Cai , Ying Xiong , Guangao Yu , Qingwen Liu , Jie Han , Xin Du , Chengshan Yuan , Qihan Zhang , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 93-105  doi: 10.12461/PKU.DXHX202408100
[Abstract](5) [FullText HTML] [PDF 1477KB](0)
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Chromatography experiments are a fundamental experimental skill that must be mastered by the students majoring in chemistry in universities. Thin-layer chromatography, column chromatography, and paper chromatography experiments constitute the basic content of organic chemistry experiments. However, the training content, requirements, and standards for chromatography experiments vary among different universities, and lead to disparities in teaching outcomes. This article puts forward basic operation and standard suggestions for organic chemical layer chromatography, column chromatography and paper chromatography experiments, hoping to provide references for domestic peers in conducting experimental teaching and scientific research practices.
Basic Operations and Specification Suggestions for Determination of Physical Constants of Organic Compounds
Ying Xiong , Guangao Yu , Lin Wu , Qingwen Liu , Houjin Li , Shuanglian Cai , Zhanxiang Liu , Xingwen Sun , Yuan Zheng , Jie Han , Xin Du , Chengshan Yuan , Qihan Zhang , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 106-121  doi: 10.12461/PKU.DXHX202503079
[Abstract](5) [FullText HTML] [PDF 1919KB](0)
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Physical constants serve as crucial indicators for identifying organic compounds and assessing their purity, with their precise determination constituting a fundamental aspect of organic chemistry experimental education. This paper comprehensively examines the significance, underlying principles, standard methodologies, operational protocols, and experimental considerations associated with the determination of key physical constants, including melting point, boiling point, refractive index, and specific rotation. Additionally, it provides an overview of contemporary instrumental techniques employed in these measurements. The authors aim to offer valuable insights and practical guidance for chemistry educators and researchers engaged in experimental teaching and scientific investigation.
Standardized Operational Guidelines for Mixed-Solvent Recrystallization in Organic Chemistry Experiment
Chengshan Yuan , Xiaolong Li , Xiuping Yang , Xiangfeng Shao , Zitong Liu , Xiaolei Wang , Yongwen Shen
2025, 40(5): 122-127  doi: 10.12461/PKU.DXHX202504073
[Abstract](5) [FullText HTML] [PDF 800KB](0)
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Mixed-solvent recrystallization is a commonly used and highly selective purification method. However, systematic operational guidelines are still lacking in current teaching, and students often encounter issues such as inappropriate solvent selection or improper techniques, resulting in failed crystallization or low purity. This paper outlines the basic principles and procedures of mixed-solvent recrystallization, clarifies key steps including solvent selection, decolorization, hot filtration, and crystallization induction, and proposes practical guidelines. These recommendations are feasible and widely applicable, offering a reference for standardizing laboratory instruction.
Suggestions on Operating Specifications of Physical Chemistry Experiment: Measurement and Control of Temperature
Wanchun Zhu , Yongmei Liu , Li Wang , Yunshan Bai , Shu'e Song , Xiaokui Wang , Zhongyun Wu , Hong Yuan , Yunchao Li , Fuping Tian , Yuan Chun , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 128-136  doi: 10.12461/PKU.DXHX202503028
[Abstract](5) [FullText HTML] [PDF 532KB](0)
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Standardized experimental procedure is a fundamental requirement for chemical experiments, and it is also an important way to cultivate a rigorous and scientific attitude. This article provides systematic suggestions on operating specifications for measuring and controlling temperature in physical chemistry experiment, which can serve as guidance and reference for students, teachers, and other relevant personnel engaged in chemical experiment learning, teaching, and research.
Suggestions on Operating Specifications of Physical Chemistry Experiment: Measurement and Control of Pressure
Zhongyun Wu , Li Wang , Xiaokui Wang , Wanchun Zhu , Yuan Chun , Fuping Tian , Yongmei Liu , Yunshan Bai , Hong Yuan , Yufeng Li , Shu'e Song , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 137-147  doi: 10.12461/PKU.DXHX202503027
[Abstract](5) [FullText HTML] [PDF 1153KB](0)
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Standardized experimental procedure is a fundamental requirement for chemical experiments, and it is also an important way to cultivate a rigorous and scientific attitude. This article provides systematic suggestions on operating specifications for measuring and controlling pressure in physical chemistry experiment, which can serve as guidance and reference for students, teachers, and other relevant personnel engaged in chemical experiment learning, teaching, and research.
Suggestions on Operating Specifications of Physical Chemistry Experiment: Measurement of Viscosity, Density and Optical Properties
Shu'e Song , Xiaokui Wang , Yongmei Liu , Wanchun Zhu , Hong Yuan , Fuping Tian , Yunshan Bai , Yunchao Li , Li Wang , Zhongyun Wu , Yuan Chun , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 148-156  doi: 10.12461/PKU.DXHX202503026
[Abstract](5) [FullText HTML] [PDF 655KB](0)
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Standardized experimental procedure is a fundamental requirement for chemical experiments, and it is also an important way to cultivate a rigorous and scientific attitude. This article provides systematic suggestions on operating specifications for measuring viscosity, density and optical properties in physical chemistry experiment, which can serve as guidance and reference for students, teachers, and other relevant personnel engaged in chemical experiment learning, teaching, and research.
Suggestions on Operating Specifications of Physical Chemistry Experiment: Measurement of Thermal Properties
Fuping Tian , Yunshan Bai , Wanchun Zhu , Yufeng Li , Yongmei Liu , Shu'e Song , Hong Yuan , Zhongyun Wu , Li Wang , Xiaokui Wang , Yuan Chun , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 157-164  doi: 10.12461/PKU.DXHX202503054
[Abstract](5) [FullText HTML] [PDF 661KB](0)
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Standardized experimental procedure is a fundamental requirement for chemical experiments, and it is also an important way to cultivate a rigorous and scientific attitude. This article provides systematic suggestions on operating specifications for measuring thermal properties in physical chemistry experiment, which can serve as guidance and reference for students, teachers, and other relevant personnel engaged in chemical experiment learning, teaching, and research.
Suggestions on Operating Specifications of Physical Chemistry Experiment: Measurement of Electrical Properties
Yunchao Li , Hong Yuan , Yuan Chun , Xiaokui Wang , Fuping Tian , Yunshan Bai , Yongmei Liu , Wanchun Zhu , Shu'e Song , Zhongyun Wu , Li Wang , Yufeng Li , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 165-177  doi: 10.12461/PKU.DXHX202503055
[Abstract](5) [FullText HTML] [PDF 949KB](0)
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Standardized experimental procedure is a fundamental requirement for chemical experiments, and it is also an important way to cultivate a rigorous and scientific attitude. This article provides systematic suggestions on operating specifications for measuring electrical properties in physical chemistry experiment, which can serve as guidance and reference for students, teachers, and other relevant personnel engaged in chemical experiment learning, teaching, and research.
Suggestions on Operating Specifications of Physical Chemistry Experiment: Measurement of Colloidal and Surface Chemical Properties, Molecular Structure and Properties
Yuan Chun , Yongmei Liu , Fuping Tian , Hong Yuan , Shu'e Song , Wanchun Zhu , Yunchao Li , Zhongyun Wu , Xiaokui Wang , Yunshan Bai , Li Wang , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 178-188  doi: 10.12461/PKU.DXHX202503053
[Abstract](5) [FullText HTML] [PDF 783KB](0)
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Standardized experimental procedure is a fundamental requirement for chemical experiments, and it is also an important way to cultivate a rigorous and scientific attitude. This article provides systematic suggestions on operating specifications for measuring colloidal and surface chemical properties, molecular structure and properties in physical chemistry experiment, which can serve as guidance and reference for students, teachers, and other relevant personnel engaged in chemical experiment learning, teaching, and research.
Recommendations for Integrating Ideological and Political Education into Chemistry Laboratory Courses for Chemistry Majors at Higher Education Institutions
Yongmei Liu , Shuyong Zhang , Shuangyan Huan , Genrong Qiang , Xia Zhang , Huan Jiao , Jiangang Li , Zhanxiang Liu , Qizhi Yao , Hongxia Fan
2025, 40(5): 189-205  doi: 10.12461/PKU.DXHX202412145
[Abstract](5) [FullText HTML] [PDF 695KB](0)
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This paper is grounded in the National Standards for Teaching Quality in Chemistry Majors and the “Guidelines for Ideological and Political Education in Chemistry Courses”, focusing on the objectives of undergraduate talent cultivation in chemistry. It analyzes the ideological and political education system, content, and design within chemistry laboratory courses, identifying key areas for reform in ideological and political teaching. The paper offers relevant recommendations and demonstrates how to achieve a cohesive integration of knowledge transmission and value guidance in chemistry laboratory instruction. This approach aims to foster students’ scientific spirit, innovative capabilities, and awareness of social responsibility, thereby serving as a valuable reference for advancing the reform of ideological and political education in chemistry experimental courses.
Suggestion for the Construction of Ideological and Political Education in Comprehensive/Design Chemical Experiment Courses in Higher Education
Hongxia Fan , Xia Zhang , Qizhi Yao , Yongmei Liu , Chengwen Chai , Wenxia Yuan , Chen Wang , Shuyong Zhang
2025, 40(5): 206-214  doi: 10.12461/PKU.DXHX202503068
[Abstract](5) [FullText HTML] [PDF 683KB](0)
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As a core practical component of chemistry majors, Comprehensive/Design chemical experiment courses not only cultivate students’ innovative thinking and complex problem-solving abilities but also serve as a natural vehicle for ideological and political education due to their openness, collaboration, and exploratory nature. This paper clarifies the ideological and political teaching objectives and connotative significance of comprehensive/design chemical experiment courses. Furthermore, it provides suggestions concerning the ideological and political knowledge system and teaching system, offering valuable insights for the construction and reform of ideological and political education in comprehensive/design chemical experiment courses for chemistry majors.
Suggestion on Enhancing of Ideological and Political Design and Integration in Undergraduate Project for Chemistry Majors
Huan Jiao , Ying Zhang , Yi Yan , Shuxian Bi , Yongmei Liu , Lingling Wei , Quanguo Zhai , Shuyong Zhang
2025, 40(5): 215-223  doi: 10.12461/PKU.DXHX202411001
[Abstract](7) [FullText HTML] [PDF 409KB](0)
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The undergraduate project is a key comprehensive training of undergraduates. Embedding ideological and political education (IPE) into the undergraduate project could fully utilize comprehensive practical links as the main channel for cultivating talents. This paper defines the objectives of incorporating IPE into the undergraduate project of chemistry-related majors, aligns these objectives with graduation requirements, presents content, teaching design, implementation and evaluation suggestions of IPE in the undergraduate project. This research offers valuable insight for the future development of enhancing IPE in the undergraduate project.
Innovative Design of Chemistry Experiment Courses with Ideological and Political Education: A Case Study of Catalytic Hydrogen Production Experiments
Yongmei Liu , Lisen Sun , Yongmei Hao , Zhanxiang Liu , Shuyong Zhang
2025, 40(5): 224-229  doi: 10.12461/PKU.DXHX202412144
[Abstract](5) [FullText HTML] [PDF 780KB](0)
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This article utilizes the catalytic hydrogen production experiment as a case study to demonstrate the systematic design of innovation-oriented experiments that encourage students to engage autonomously in practical activities. It provides students with opportunities to apply catalytic technology and kinetic characterization techniques to address real-world challenges in green hydrogen production, thereby enhancing their ability to translate theoretical knowledge into practical application. Furthermore, the study emphasizes the importance of fostering awareness of sustainable development in national green energy initiatives, while also cultivating students’ innovative thinking and problem-solving skills. The article aims to present effective strategies for integrating ideological and political content into experimental design, practical execution, and outcome evaluation. It serves as a valuable reference for incorporating ideological and political education into innovation-oriented experiments within chemistry-related disciplines, ultimately contributing to the development of talent with both innovative spirit and practical capabilities.
Exploration and Practice of the Construction of the Basic Operation Standard of Organic Chemistry Experiment Based in Virtual Teaching Research
Houjin Li , Zhanxiang Liu , Yuan Zheng , Shuanglian Cai , Jie Han , Ying Xiong , Xingwen Sun , Chengshan Yuan , Guangao Yu , Qingwen Liu , Lin Wu , Qihan Zhang , Xin Du , Jianrong Zhang , Shuyong Zhang
2025, 40(5): 230-237  doi: 10.12461/PKU.DXHX202502064
[Abstract](3) [FullText HTML] [PDF 3571KB](0)
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This paper analyzes the problems and their causes in the guidance of operation specifications in current organic chemistry experiment teaching. It points out the importance of constructing experimental operation specifications, the principles for formulating experimental operation specifications. Moreover, it elaborates in detail on the content, methods, writing requirements of the basic operation specifications of organic chemistry experiments that have been carried out, as well as the achievements already obtained. This paper helps peers gain a more comprehensive understanding of the basic operation specifications of organic chemistry experiments. It also assists peers in guiding students to master standardized and safe experimental operation skills in future teaching, so as to cultivate high-quality chemistry professionals.
Promoting an All-English Teaching Approach in the Chemistry English Curriculum to Enhance Internationalization
Yuan Yang , Jian Zhang , Shaomin Shuang
2025, 40(5): 238-243  doi: 10.12461/PKU.DXHX202403079
[Abstract](5) [FullText HTML] [PDF 2328KB](0)
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Internationalizing academic curricula is crucial in meeting the demands for global talent and fostering students with enhanced international competitiveness. This study explores the role of advancing an all-English teaching approach in the Chemistry English curriculum to promote internationalization. By analyzing the current landscape and challenges of traditional Chemistry English education alongside the implementation of all-English teaching in our university’s chemistry courses, this paper proposes targeted measures for educational reform. These include improvements in teaching philosophy, methodologies, curriculum structure, resources, and content delivery. The article underscores the importance of adopting an all-English approach in enhancing the internationalization of the Chemistry English curriculum and discusses how these reforms can elevate students’ comprehensive skills and global competitiveness.
Exploring the Full Process of a Research-Based Teaching Model through the Deep Integration of Theory and Practice: A Case Study of the Self-Designed Scheme for “Determination of Total Acid Content in White Vinegar”
Liping Wang , Huanfeng Wang , Yuling Li , Lingchuan Li , Xiaojing Li , Huifeng Chen , Bowen Ji , Linna Wang
2025, 40(5): 244-251  doi: 10.12461/PKU.DXHX202406035
[Abstract](4) [FullText HTML] [PDF 1846KB](0)
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This study employs research-based methods to deeply integrate theoretical knowledge with practical applications, leading to a multi-dimensional reform of the research-based teaching model in the analytical chemistry course for first-year undergraduate students at our university. This approach has been shown to effectively enhance students' active learning capabilities, foster their skills in information processing and problem-solving, and facilitate the transition from surface learning to deep learning. The findings aim to offer insights for implementing research-based teaching strategies for lower-year students with limited systematic knowledge of chemistry and underdeveloped research skills.
Exploring “Magic Teaching” as a Means to Integrate Organic Chemistry Experiments with the “Industry-University-Research” Model
Yi-Lin Xie , Jian-Ji Zhong , Qing-Xiao Tong , Jing-Xin Jian
2025, 40(5): 252-260  doi: 10.12461/PKU.DXHX202407024
[Abstract](5) [FullText HTML] [PDF 4372KB](0)
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This study addresses several challenges in organic chemistry experiment courses, including complex theoretical concepts, monotonous practical activities, limited curriculum engagement, and insufficient ideological content. By connecting the historical development of organic chemistry with real-life narratives, we infuse the experimental course with a sense of mysterious “magic”, thereby stimulating students’ interest in learning and exploration. We propose a teaching model that integrates “industry-university-research” through three dimensions: theory, practice, and application. Additionally, we intertwine the “magic” narratives with ideological components aimed at moral education, subtly instilling correct scientific concepts in students’ minds.
Promote the Training of Top Talents by Optimizing the Theoretical Computational Chemistry Curriculum System
Qian Peng , Pengfei Yao , Zicong Wang , Xiufang Xu , Hongwei Sun
2025, 40(5): 261-267  doi: 10.12461/PKU.DXHX202408012
[Abstract](5) [FullText HTML] [PDF 780KB](0)
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Recognizing the significant role of theoretical computational chemistry in advancing chemistry and related fields, the chemistry teaching team in Nankai University has developed a training model as part of the “Pilot Plan for Cultivating Top Students in Basic Disciplines”. This model centers around an “Introduction to Computational Chemistry” course, integrating theory, practice, and cutting-edge research to enhance the cultivation of top talents. Over four years of teaching practice, the team has explored and refined aspects of training modes, curriculum design, and interdisciplinary integration. Student feedback data indicates that this optimized curriculum system significantly fosters the development of outstanding talent in the field.
Teaching Design and Reflection on the “Osmotic Pressure of Solutions” in Medical Chemistry
Tiantian Dai , Xi Yang
2025, 40(5): 268-275  doi: 10.12461/PKU.DXHX202411032
[Abstract](3) [FullText HTML] [PDF 1569KB](0)
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This paper presents an overview of the teaching design and considerations for the chapter on “osmotic pressure of solutions” in medical chemistry courses. The chapter covers topics such as osmotic phenomena, osmotic concentration, the calculation of solution osmotic pressure, and its applications in medicine. The calculation of osmotic concentration and osmotic pressure presents significant challenges for most students. To address this, the teaching design is centered on a problem-based approach, incorporating real-life phenomena and case studies. The instructional sequence includes creating problem scenarios, experimental exploration, computational derivation, knowledge transfer and application, knowledge extension, and integrating ideological and political education. By weaving computational examples and medical case studies throughout the course, the problem-oriented teaching approach enhances student engagement and helps them grasp the key concepts and content of the chapter during classroom instruction, ultimately achieving the teaching objectives.
Practice of Ideological and Political Education in Organic Chemistry Laboratory Courses under the OBE Framework: A Case Study of Berberine Extraction
Huicheng Yang , Qianhong Sun
2025, 40(5): 276-282  doi: 10.12461/PKU.DXHX202410091
[Abstract](5) [FullText HTML] [PDF 888KB](0)
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This paper examines the reform of ideological and political practice in organic chemistry laboratory courses based on the principles of Outcome-Based Education (OBE). It delineates the educational objectives of the organic chemistry laboratory within this framework and identifies the ideological and political elements embedded in the experiments. Furthermore, this study enhances the evaluation system for ideological and political education in the organic chemistry laboratory course by incorporating additional indicators for assessing ideological and political literacy. Finally, through a case analysis of the teaching design, the paper illustrates the outcomes of these teaching practices, offering valuable insights for integrating ideological and political education into the curriculum and fostering students’ comprehensive competencies.
Curriculum Reform of “Chemical Composition Analysis of Materials” under Background of First-Class Discipline Construction
Yuan Zhuang , Wenhui Li , Jie Li
2025, 40(5): 283-290  doi: 10.12461/PKU.DXHX202407070
[Abstract](5) [FullText HTML] [PDF 1342KB](0)
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This study implements teaching reforms for the “Chemical Composition Analysis of Materials” course in alignment with the talent cultivation objectives of first-class discipline construction. We developed an integrated pedagogical framework combining online-offline learning with theoretical-practical instruction, incorporating sophisticated instrumentation into experimental teaching. The established “classroom learning - online self-study-group design - experimental implementation” teaching system is supported by a multidimensional evaluation approach. This reform emphasizes student-centered learning while integrating ideological and political elements, effectively enhancing students' professional competencies, scientific thinking, and innovation capabilities through design-oriented experiments.
Design and Reflections on the Integration of Artificial Intelligence in Physical Chemistry Laboratory Courses
Meirong Cui , Mo Xie , Jie Chao
2025, 40(5): 291-300  doi: 10.12461/PKU.DXHX202412015
[Abstract](3) [FullText HTML] [PDF 1104KB](0)
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The digitalization of education represents a significant breakthrough for China in exploring new pathways for educational development, and the integration of artificial intelligence into education is an inevitable trend. This article analyzes the design principles for incorporating artificial intelligence into physical chemistry laboratory courses, based on the exploration of intelligent teaching models. It presents a concrete vision for an artificial intelligence-enabled physical chemistry laboratory platform and evaluates the initial practical outcomes at our institution. This research provides a novel perspective for advancing the transformation of traditional chemistry laboratory teaching methods towards a more intelligent approach.
Organic Electrochemistry and Its Integration into Chemistry Teaching
Hong Yan , Wenfeng Wang , Keyin Ye , Yaofeng Yuan
2025, 40(5): 301-310  doi: 10.12461/PKU.DXHX202407027
[Abstract](5) [FullText HTML] [PDF 916KB](0)
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Organic electrochemistry has been recognized as one of the top ten emerging technologies in chemistry by International Union of Pure and Applied Chemistry (IUPAC) in 2023. As a crucial branch of fundamental chemistry in undergraduate education, electrochemistry is primarily addressed in the context of inorganic chemistry (specifically redox reactions) and physical chemistry (in relation to electrolyte solutions). However, references to organic electrochemistry in undergraduate curricula are notably scarce. This article presents recent research trends in organic electrochemistry and discusses considerations for incorporating organic electrochemistry into undergraduate chemistry teaching.
Electrochemical Transformation of Organosulfur Compounds
Yongjian Zhang , Fangling Gao , Hong Yan , Keyin Ye
2025, 40(5): 311-317  doi: 10.12461/PKU.DXHX202407035
[Abstract](6) [FullText HTML] [PDF 454KB](1)
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The synthesis and transformation of organosulfur compounds hold significant theoretical and practical value. However, the coverage of organosulfur compounds in fundamental organic chemistry textbooks is limited. This article begins with a brief overview of the key concepts related to organosulfur compounds as presented in the basic organic chemistry course. It then compares and discusses recent advancements in the electrochemical transformations of these compounds. This study aims to enhance the understanding of chemistry major students regarding the cutting-edge developments in organic electrochemistry as it pertains to organosulfur chemistry.
Advances in the Application and Preparation of Rhodanine and Its Derivatives
Siran Wang , Yinuo Wang , Yilong Zhao , Dazhen Xu
2025, 40(5): 318-327  doi: 10.12461/PKU.DXHX202407033
[Abstract](6) [FullText HTML] [PDF 569KB](0)
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Rhodanine and its derivatives are privileged scaffolds commonly found in synthetic compounds. Molecules containing this structural motif often display remarkable biological and pharmacological activities, including antidiabetic, antibacterial, anticancer, and anti-HIV effects. Additionally, they serve as optoelectronic materials, dyes, and analytical reagents. This article provides an overview of the properties and applications of rhodanine and its derivatives, summarizes recent advancements in their preparation methods, and discusses future prospects for research in this field.
Photocatalytic Journey of Perylene Diimides in a Competitive Arena
Jiatong Hu , Qiyi Wang , Ruiwen Tang , Jiajing Feng
2025, 40(5): 328-333  doi: 10.12461/PKU.DXHX202407015
[Abstract](5) [FullText HTML] [PDF 989KB](0)
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Perylene diimides (PDIs) and their derivatives are organic semiconductor materials with exceptional optoelectronic properties, extensively researched and applied in high-tech fields such as organic photovoltaics, organic light-emitting diodes, and organic field-effect transistors in recent years. Their advantages—such as low cost, strong visible light absorption, ease of band edge modulation, and the ability to form ordered supramolecular structures—have positioned them as rising stars in photocatalysis. This article incorporates elements of Chinese traditional culture and employs a personified approach in the form of a martial arts tournament to illustrate the structures and characteristics of PDI materials. By comparing the photocatalytic performance of PDIs with other photocatalytic materials, the paper highlights the advantages and challenges of PDIs in photocatalysis and offers insights into their promising development prospects in this field.
Application of Knoevenagel Reaction in Organic Chemistry Teaching
Shuixing Dai , Jilei Jiang , Yuxiao Wang , Jinqi Hu , Minghua Huang
2025, 40(5): 334-341  doi: 10.12461/PKU.DXHX202405208
[Abstract](5) [FullText HTML] [PDF 1014KB](0)
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This study integrates fundamental organic chemistry concepts, including the Knoevenagel condensation reaction, with cutting-edge research in organic solar cells. Through a laboratory experiment, students synthesized a wide-bandgap fused-ring electron acceptor material, A831. Analysis of the experimental data demonstrated that diminishing the electron-withdrawing ability of the terminal groups elevated the material’s lowest unoccupied molecular orbital (LUMO) energy level, thereby enhancing the voltage output of the organic solar cells. This experiment cultivates students’ ability to apply foundational knowledge to solve research problems, embodying the educational philosophy of “fundamental knowledge – practical application”. It is particularly suitable as a comprehensive course for senior undergraduate students.
Design and Practice of a Comprehensive Teaching Experiment for Preparing Biomass Carbon Dots from Rice Husk
Kuaibing Wang , Feifei Mao , Weihua Zhang , Bo Lv
2025, 40(5): 342-350  doi: 10.12461/PKU.DXHX202407042
[Abstract](5) [FullText HTML] [PDF 1765KB](0)
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This innovative comprehensive experiment aims to develop a teaching concept based on “green chemistry” by integrating theoretical knowledge of literature retrieval, inorganic synthesis, instrumental analytical chemistry and electrochemistry. Emphasizing chemical recycling, reuse and repurposing of waste, the experiment deepens students’ understanding of basic chemistry principles, promotes innovative thinking, and enhances their innovation consciousness. Taking carbon quantum dots and energy storage as the entry point, the research focuses on carbon quantum dots obtained from the hydrothermal reaction of rice husk, aiming to explore the relationship between their structure and properties. Through experimental design, result analysis and collaborative discussion, students can gain insights into the interdisciplinary potential of “agriculture and science” integration and the fusion of science and education. This approach effectively improves students’ practical and innovation abilities, and enhances their academic confidence.
Determination of the Michaelis Constant for Gold Nanozyme-Catalyzed Decomposition of Hydrogen Peroxide
Yu Dai , Xueting Sun , Haoyu Wu , Naizhu Li , Guoe Cheng , Xiaojin Zhang , Fan Xia
2025, 40(5): 351-356  doi: 10.12461/PKU.DXHX202407052
[Abstract](4) [FullText HTML] [PDF 688KB](0)
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In recent years, gold nanoparticles (AuNPs) have been identified as possessing nanozyme properties, enabling them to mimic the catalytic activity of natural peroxidases in the decomposition of hydrogen peroxide (H2O2). In this study, AuNPs were synthesized using gelatin as a reducing agent, and the Michaelis constant for the AuNP-catalyzed decomposition of hydrogen peroxide was determined using UV-Vis spectroscopy. Integrating the innovative concept of “nanozyme” into a physical chemistry kinetics experiment designed for undergraduate students not only enhances their comprehensive skills but also fosters their interest in chemical experimentation and instills a sense of national pride.
Electrochemical Synthesis of 2,5-Diphenyl-1,3,4-Oxadiazole: A Recommended Comprehensive Organic Chemistry Experiment
Shuhui Li , Rongxiuyuan Huang , Yingming Pan
2025, 40(5): 357-365  doi: 10.12461/PKU.DXHX202407028
[Abstract](5) [FullText HTML] [PDF 1657KB](0)
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This experiment employs an electrochemical synthesis method to produce 2,5-diphenyl-1,3,4-oxadiazole from benzoylhydrazine. The structure of the synthesized product is identified and characterized using analytical techniques, including NMR, infrared spectroscopy, and melting point determination. In comparison to traditional organic synthesis methods, the electrochemical approach aligns with green chemistry principles, offering advantages such as simplicity, mild reaction conditions, and high yield. This experiment encourages students, who have mastered fundamental organic laboratory techniques, to explore cutting-edge electrochemical synthesis methods and gain insights into the application of electrochemistry in organic synthesis. Additionally, it fosters students’ interest in scientific research and innovative thinking, thereby enriching the content of basic organic chemistry education.
Collaborative Science and Education Based Experimental Design in Organic Chemistry: A Case Study of the Nucleophilic Substitution Reaction of 2-Hydroxymethyl-4,6-Di-Tert-Butylphenol
Aiyi Xin , Jiawei Li , Xinyang Ran , Chuanjiang Fu , Zhiguo Wang
2025, 40(5): 366-375  doi: 10.12461/PKU.DXHX202407031
[Abstract](3) [FullText HTML] [PDF 1137KB](0)
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The experimental phenomena observed in gas-liquid-solid reactions serve to stimulate students’ interest in learning. The intricate connections between gas generation, drying, and tail gas treatment equipment encourage students to adopt a mindset of understanding the sequence and significance of processes. Through the separation, purification, and characterization of products, students develop comprehensive skills in organic synthesis. Standardizing the use of concentrated sulfuric acid and managing hazardous gas treatments enhance students’ awareness of emergency protocols and environmental responsibility. Finally, by extending the experimental focus to a series of related reactions, students are guided to transition from theoretical knowledge to practical application.
Teaching Reform of Benzoin Oxidation Experiment in the Context of Green Pharmaceutical Chemistry
Meihong Luo , Hongyu Wang
2025, 40(5): 376-382  doi: 10.12461/PKU.DXHX202411055
[Abstract](6) [FullText HTML] [PDF 1040KB](0)
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Green chemistry has emerged as a pivotal focus in organic synthesis and pharmaceutical development. This paper introduces a photocatalytic benzoin oxidation experiment grounded in green chemistry principles. The experiment utilizes oxygen from the air as the oxidant, 9-mesityl-10-methylacridinium perchlorate as the photocatalyst, triethylenediamine as the base, and chloroform as the solvent, subjected to irradiation by a 456 nm LED for 2 h. By optimizing the experimental conditions, we established the optimal reaction parameters, which were subsequently implemented in undergraduate laboratory courses, thereby integrating scientific research with education.
Application and Exploration of Old University Scientific Instruments in the Cultivation of Undergraduates’ Innovative Ability
Guangtao Zhao , Zonghuai Liu
2025, 40(5): 383-390  doi: 10.12461/PKU.DXHX202407047
[Abstract](5) [FullText HTML] [PDF 1223KB](0)
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This paper discusses the key role and potential value of old university scientific instruments in the cultivation of undergraduates’ innovative ability. Combined with the cultivation objectives of “double first-class” universities, the paper analyzes the status quo of the reuse of old scientific instruments, and puts forward targeted practical measures and ways for future exploration. Through refined management and innovative utilization, the old scientific instruments can be renewed in their application, provide solid support for the cultivation of undergraduates’ innovative ability, and help more high-quality talents with innovative quality and practical ability to stand out.
Analysis of the Report Generated by the QuadraSorb evo BET Surface Area Analyzer
Xia Shu , Longtian Sima , Jiali Wang , Jiacheng Chu , Xieyidai·Yusunjiang , Mubareke·Maimaitijiang , Yingwei Lu , Yan Wang
2025, 40(5): 391-400  doi: 10.12461/PKU.DXHX202411013
[Abstract](3) [FullText HTML] [PDF 2181KB](0)
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This study conducts an in-depth analysis of the typical specific surface area analysis reports generated by the BET Assistant software, utilizing actual measurement data from the QuadraSorb evo specific surface area and pore size analyzer. Key aspects examined include the interpretation of relevant test parameters, the rationale behind the BET Assistant's point selection, and the process of fitting the linear equation. Additionally, the study highlights critical considerations for sample preparation prior to testing. This analysis provides valuable and targeted guidance for the accurate use of the specific surface area analyzer and enhances the understanding of the report content.
2025, 40(5): 401-402
[Abstract](6) [FullText HTML] [PDF 224KB](0)
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