Citation: Saisai Chen, Zhi Hong, Xiaoyu Huang, Xiaoqing Lv, Zongyang Li, Xinrou Hu, Xinying Ruan, Qianyan Yu. Syntheses of Dithiocarbamates Catalyzed by KF/nano-γ-Al₂O₃ under Microwave Irradiation[J]. Chemistry, ;2021, 84(6): 596-603. shu

Syntheses of Dithiocarbamates Catalyzed by KF/nano-γ-Al₂O₃ under Microwave Irradiation

School of Pharmaceutical and Materials Engineering, Taizhou University, Taizhou, 318000

Corresponding author: Zhi Hong, zhihong@tzc.edu.cn
Received Date: 16 December 2020
Accepted Date: 8 January 2021

Figures(5)

In this paper, an efficient method for the synthesis of dithiocarbamates under microwave irradiation condition with KF/nano-γ-Al₂O₃ catalyzed Michael addition of electron-deficient alkenes, amines and carbon disulfide in the PEG-400 solution was developed with yields of 76.5% to 91.6%. Meanwhile, the effects of the catalyst, solvent, microwave power, reaction time on the reaction were investigated, and the optimum conditions of the experiment were determined. This method has the advantages of short reaction time, high yield and environmental friendliness. In addition, KF/nano-γ-Al₂O₃ catalyzed one-pot synthesis of dithiocarbamates from benzaldehyde, ketones, amines and carbon disulfide in PEG-400 solution under microwave irradiation was investigated. The yields were 73.4%~82.8%.
- Dithiocarbamates,
- Microwave irradiation,
- Michael addition,
- KF/nano-γ-Al₂O₃
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Syntheses of Dithiocarbamates Catalyzed by KF/nano-γ-Al₂O₃ under Microwave Irradiation