Citation: Wang Kun, Zou Long, Liu Genyan, Tan Yi. Recent Development in Syntheses of Moxifloxacin and Its Impurities[J]. Chemistry, ;2018, 81(5): 414-424. shu

Recent Development in Syntheses of Moxifloxacin and Its Impurities

Wang Kun ^1,4 ,
Zou Long ² ,
Liu Genyan ^3,, ,
Tan Yi ^4,,

1.
Changjiang Polytechnic, Wuhan 430074
2.
Quality and Technical Supervision Center of Jingmen, Jingmen 448124
3.
School of Chemical Engineering & Pharmacy, Wuhan Institute of Technology, Wuhan 430073
4.
School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071

Corresponding author: Liu Genyan, liugenyan@wit.edu.cn Tan Yi, tan@whu.edu.cn
Received Date: 7 December 2017
Accepted Date: 6 March 2018

Figures(1)

Moxifloxacin is a fourth-generation quinolone antibiotic, which has broad antibacterial spectrum, strong effect, low toxicity, so it is widely used in clinics. Moxifloxacin impurities were produced during process of synthesis and storage, the impurities must be controlled respectively to ensure the security and effect of the moxifloxacin drug. In this paper, the recent development in synthesis of moxifloxacin and its impurities was reviewed.
- Moxifloxacin,
- Impurity,
- Synthesis
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