Citation: Yuan LI, Jian Dong SHI, Yuan Jing ZHANG, Sheng JIN, Qi Yi XING. Synthesis and Steric Structure of 1, 5-Benzothiazepine-Phenyl-β-Lactams[J]. Chinese Chemical Letters, ;1999, 10(1): 23-26. shu

Synthesis and Steric Structure of 1, 5-Benzothiazepine-Phenyl-β-Lactams

a Department of Chemistry, Hebei Normal University, Shijiazhuang 050016;Shijiazhuang Teachers College 050041;
b Beijing institute of Radiation Medicine, Beijing 100850;
c Institute of Chemistry and Molecular Engineering, Peking University, Beijing 100871

Received Date: 3 July 1998

1, 5-Benzothiazepines 1 react with phenylacetyl chloride to give the title compounds. The structures of these new compounds were confirmed by elemental analysis, ¹H NMR, ^l3C NMR and MS spectroscopy, and their configuration (the mutual positions of the substituents relative to the β-lactam ring) and conformation of the compounds were determined by X-ray crystal analysis.
- 1, 5-benzothiazepine,
- β-lactam,
- stereospecific reaction
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