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Citation: Su Changhui, Liu Xia, Ding Zhiyuan, Cui Kai, Ma Jiejie. Synthesis of Methoxy Polyethylene Glycol-1, 2-Distearoyl-glycero-3-phosphoethanolamine[J]. Chemistry, ;2017, 80(3): 304-306. shu

Synthesis of Methoxy Polyethylene Glycol-1, 2-Distearoyl-glycero-3-phosphoethanolamine

Su Changhui ^1, ,
Liu Xia ² ,
Ding Zhiyuan ¹ ,
Cui Kai ¹ ,
Ma Jiejie ¹

1.
Chemistry and Life Science College, Nanjing University Jinling College, Nanjing 210089
2.
College of Enviroment and Ecology, Jiangsu Open University, Nanjing 210036

Received Date: 5 May 2016
Accepted Date: 20 October 2016

Figures(1)

1, 2-Distearoyl-glycero-3-phosphoethanolamine (DSPE) was synthesized with glycerol-1, 2-distearate, phosphorus oxychloride and 2-aminoethanol as starting materials. Subsequently, reaction of DSPE with N, N'-carbonyldiimidazole (CDI) and mPEG2000 gave the target compound mPEG2000-DSPE, which was characterized by IR analysis, ¹H NMR spectroscopy and mass spectrometry.
- Methoxy polyethylene glycol,
- N, N'-carbonyldiimidazole,
- 1, 2-Distearoylglycerol-phosphoe-thanolamine,
- Synthesis
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