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Citation:
Peng LI, Jie Cheng XU. 1-Ethyl-2-Fluoro Pyridinium Salt:A Highly Efficient Coupling Reagents for Sterically Hindered Peptide Synthesis[J]. Chinese Chemical Letters,
;2000, 11(5): 377-380.
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1-Ethyl-2-fluoropyridinium tetrafluoroborate(FEP)was shown to be a very efficient coupling reagent for the synthesis of the hindered peptide with fast reaction speed,low racemization and good yields.
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Keywords:
- FEP,
- peptide,
- racemization,
- reactivity
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