Citation: Jian Xin CHEN, Chi Zhong XIA, Jin Pei CHENG. Synthesis of an N⁵N¹⁰-methenyltetrahydrofolate Model and Its Substituted One-Carbon Unit Transfer Reaction[J]. Chinese Chemical Letters, ;1996, 7(9): 803-806. shu

Synthesis of an N⁵N¹⁰-methenyltetrahydrofolate Model and Its Substituted One-Carbon Unit Transfer Reaction

a Datong Medical College, Datong, Shanxi, 037008;
b Department of Chemistry, Shanxi University, Taiyuan 030006;
c Nankai University, Tianjin 300071

Received Date: 2 April 1996

Fund Project: This investigation was supported by the National Natural Science Foundation of China.

Substituted imidazolinium salt, l, 2-dimethyl-3-(p-methoxybenzenesulfonyl) imidazolinium iodide, as a tetrahydrofolate model in terms of the ability to transfer a substituted one-carbon unit (ethylidyne, nitromethylethylidene), can react with a variety of mono- and bifunctional nucleophiles and lead to some carboline alkaloids and other heterocyclic compounds.
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