Citation: Chen Sihong, Liu Dianqing, Tan Yunfei, Zheng Xiaogang. Research Progresses in Plankinidines and Analogous Alkaloids[J]. Chemistry, ;2017, 80(8): 725-733. shu

Research Progresses in Plankinidines and Analogous Alkaloids

1.
Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331
2.
Chongqing Prometheuso Institute of Chemical Science & Technology, Chongqing 401331
3.
Neijiang Normal University, Neijiang 641100

Corresponding author: Zheng Xiaogang, zhengxg123456@163.com
Received Date: 24 December 2016
Accepted Date: 8 April 2017

Figures(6)

Plakinidines and analogues are the pyrrolacridine and pyridoacridine polycyclic alkaloids that are isolated from ocean mollusks. And plakinidines are the first class of pyrrolacridine containing alkaloids found in marine extracts, some of which have good biological activities such as anti-cancer and anti-parasite. In this paper, studies on the extraction, isolation, structural elucidation, bio-activity and chemical synthesis of plakinidines and analogous alkaloids are reviewed.
- Plakinidines,
- Alkaloids,
- Biological activity,
- Chemical synthesis
1. [1]
  A J Weinheimer, R L Spraggins. Tetrahed. Lett., 1969, 59:5185~5188.
2. [2]
  A F Fitzpatrick, A M Wynalda. Biochemistry, 1981, 20(21):6129~6134.
3. [3]
  M T Ehrman, J D Barlow, J P Hylands. J. Chem. Inf. Model., 2007, 47(2):264~278.
4. [4]
  A F Fitzpatrick. Anal. Chem., 1978, 50(1):47~52.
5. [5]
  F J Shimitz, T Yasumoto. J. Nat. Prod., 1991, 54(6):1469~1490.
6. [6]
  J R Andersen, J D Faulkner, H C He et al. J. Am. Chem. Soc., 1985, 107(19):5492~5495.
7. [7]
  N Lindquist, W Fenical, V Duyne et al. J. Org. Chem., 1988, 53(19):4570~4574.
8. [8]
  W D Inman, M O'Neill-Johnson. J. Am. Chem. Soc., 1990, 112(1):1~4.
9. [9]
  R R West, C L Mayne, C M Ireland. Tetrahed. Lett., 1990, 31:3271~3274.
10. [10]
  C J Smith, D A Venables, C Hopmann et al. J. Nat. Prod., 1997, 60:1048~1050.
11. [11]
  P W Ford, B S Davidson. J. Nat. Prod., 1997, 60:1051~1053.
12. [12]
  P Ralifo, L Sanchez, N C Gassne et al. J. Org. Chem., 2007, 70:95~99.
13. [13]
  J Kim, E O Pordesimo, S I Toth et al. J. Nat. Prod., 1993, 56:1813~1816.
14. [14]
  V Sharma, P C Sharma, V Kumar. J. Adv. Res., 2015, 6:63~71.
15. [15]
  F J Schmitz, S K Agarwal, S P Gunasekera et al. J. Am. Chem. Soc., 1983, 105:4835~4836.
16. [16]
  A Plubrukarn, B S Davidson. J. Org. Chem., 1998, 63:1657~1659.
17. [17]
  G Koren-Goldshlager, M Aknin, E M Gaydou et al. J. Org. Chem., 1998, 63:4601~4603.
18. [18]
  G Koren-Goldshlager, M Aknin, E M Gaydou et al. J. Nat. Prod., 2000, 63:830~831.
19. [19]
  A Rudi, Y Kashman. J. Org. Chem., 1989, 54:5331~5337.
20. [20]
  D C Jenkins, R Armitage, T S Carrington. Zeitschrift für Parasitenkunde, 1980, 63:261~269.
21. [21]
  Z Thale, T Johnson, K Tenney et al. J. Org. Chem., 2002, 67:9384~9391.
22. [22]
23. [23]
  Y Kitahara, T Mizuno, A Kubo. Tetrahedron, 2004, 60:4283~4288.
24. [24]
  G Conte, A J Bortoluzzi, H Gallardo. Synthesis, 2006, 23:3945~3947.
25. [25]
  J Bolger, A Gourdon, E Ishow et al. Chem. Commun., 1995, 17:1799~1800.
26. [26]
  A F M Motiur Rahman, Y Kwon, Y Jahng et al. Heterocycles, 2005, 65:2777.
27. [27]
  L Guo, B Qiu, G Chen. Anal. Chim. Acta, 2007, 588:123~130.
28. [28]
  C Metallinos, F B Barrett, Y Wang et al. Tetrahedron, 2006, 62:11145~11157.
29. [29]
  R Elvira, Y Z Hu, F Bouvier et al. Inorg. Chem., 2001, 40:2541~2546.
30. [30]
  Y Z Hu, Q Xiang, R P Thummel. Inorg. Chem., 2002, 41:3423~3428.
31. [31]
  S Gladiali, G Chelucci, M S Mudadu et al. J. Org. Chem., 2001, 66:400~405.
32. [32]
  D V Kravchenk, V V Kysil, A P Ilyn. Bioorg. Med. Chem. Lett., 2005, 15:1841~1845.
33. [33]
  D V Kravchenk, V M Kysil, S E Tkachenk et al. Eur. J. Med. Chem., 2005, 40:1377~1383.
34. [34]
  E Campaigne, J H Hutchinson. J. Hetercyc. Chem., 1970, 7:655~659.
35. [35]
  J Parrick, A Yahya, A S Ijaz et al. J. Chem. Soc., Perkin Transac., 1989, 11:2009~2015.
36. [36]
  Y Kitahara, F Tamura, A Kubo. Tetrahed. Lett., 1997, 38:4441~4442.
37. [37]
  E Delfourne, F Darro, N Bontemps-Subielos et al. J. Med. Chem., 2001, 44:3275~3282.
38. [38]
  M Ȃlvarez, L Feliu, W Ajanaa et al. Tetrahedron, 2000, 56:3703~3708.
39. [39]
40. [40]
41. [41]
  K Tatsuta, S Hosokawa. Chem. Rev., 2005, 105:4707~4729.
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