Citation: Shu Chun LI, Li Min NIU, Hui LI, Zhong Jun LI, Qing LI. Synthesis of RGD-aPEG-lactoside, a Potential Anti-metastasis Glycoconjugate[J]. Chinese Chemical Letters, ;2004, 15(5): 532-534. shu

Synthesis of RGD-aPEG-lactoside, a Potential Anti-metastasis Glycoconjugate

Department of Chemical Biology, School of Pharmaceutical Sciences and National Research Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083

Received Date: 28 July 2003

The adhesive interaction between tumor cells and host cells or the extra cellular matrix plays a crucial role in metastasis. Due to the anti-metastasis effects of RGD (arginyl-glycyl-aspartic acid) and some oligosaccharides, RGD-aPEG-Lactoside was prepared which will be used on anti-metastasis.
- RGD,
- lactose,
- PEG,
- anti-metastasis
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