Citation: Xiao Ming FENG, De Chao ZENG, Zhi Li, Yao Zhong JIANG. Resolution of Spiro[4.4]nonane-1,6-dione by Chiral Inclusion Complexation[J]. Chinese Chemical Letters, ;1999, 10(7): 559-562. shu

Resolution of Spiro[4.4]nonane-1,6-dione by Chiral Inclusion Complexation

Union Laboratory of Asymmetric Synthesis, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041

Received Date: 7 December 1998

Fund Project: We thank the National Natural Science Foundation of China (No. 29832020) and the Union Laboraton of Asy mmetric Sy nthesis in Chengdu for financial support of this study .

The racemic spiro[4.4]nonane-l,6-dione was efficiently resolved through an enantioselective inclusion complexation using chiral host BINOL by simple recrystallization with 31.9~38.4% yield and 100%ee.
- Resolution,
- chiral inclusion complexation,
- enantioselectivity
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