Citation: Liu Lang, Feng Jundong, Sheng Yingzhong, Wang Jing, Qiu Liang. Preparations, Characterizations and Antibacterial Activities of High-Valence Silver Complexes[J]. Chemistry, ;2017, 80(4): 378-384. shu

Preparations, Characterizations and Antibacterial Activities of High-Valence Silver Complexes

  • Corresponding author: Feng Jundong, jundongfeng@nuaa.edu.cn
  • Received Date: 16 July 2016
    Accepted Date: 16 November 2016

Figures(8)

  • Three fairly stable high-valence silver complexes [AgEn(BigH)2]2(SO4)3·7H2O (3), [Ag(Py)2(N2)2](OH)2 (4) and [Ag(2-Apy)3(OH)](HSO4)·H2O (5) have been synthesized with ethylenebisbiguanide, pyridine and pyridine derivative as ligands. The products were characterized by IR, elemental analysis and X-ray photoelectron spectroscopy. The growth-inhibitory curves and the minimal inhibitory concentration (MIC) were applied to evaluate the antibacterial ability of complexes, and the photostability of complexes was detected. The results showed that all the complexes begin to inhabit the growth of test bacteria at very low concentration of 0.5 μg/mL, and the MIC values for E.coli are 10, 5, and 5 μg/mL respectively, the MIC values for S.aureus are 40, 20, and 20 μg/mL respectively, indicating the synthesized high-valence silver complexes possess an excellent antibacterial activity. Besides, all the complexes have better antibacterial activity to E.coli than S.aureus.
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