Citation: Guo Hong LI, Yue Mao SHEN, Ke Qin ZHANG. A New Saponin Transformed from Ginsenoside Rh_l by Bacillus subtilis[J]. Chinese Chemical Letters, ;2005, 16(3): 359-361. shu

A New Saponin Transformed from Ginsenoside Rh_l by Bacillus subtilis

1.
Laboratory for Conservation and Utilization of Bio-resource, Yunnan University, Kunming 650091;
2.
The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204

Received Date: 18 February 2004

Fund Project: The authors gratefully acknowledge support for this work of the National Natural Science Foundation (No. 20362010) and are grateful to Mr. Y. N. He and Ms. H. L. Liang in the State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, for measuring NMR and MS data, respectively.

A novel saponin was isolated from the transformed products of ginsenoside Rh₁ by Bacillus subtilis. It's structure was determined to be 3-O-β-D-glucopyranosyl-6-O-β-D-glucopyranosyl-20 (S)-protopanaxatriol on the basis of the spectral data.
- Ginsenoside Rh₁,
- novel saponin,
- biotransformation.
1. [1]
  Zhiqiang Cui , Dongxiang Zhang , Yanru Huang , Chunyu Shao , Yiming Zhang , Changliang Sun , Xin-Dong Jiang , Xiaohong Sun , Qinghuan Xiao . Novel 1-phenylethyl-containing aza-BDOIPY for phototherapy and simultaneous monitoring of tumor immune microenvironment reprogramming. Chinese Chemical Letters, 2025, 36(7): 110460-. doi: 10.1016/j.cclet.2024.110460
2. [2]
  Bairu Meng , Zongji Zhuo , Han Yu , Sining Tao , Zixuan Chen , Erik De Clercq , Christophe Pannecouque , Dongwei Kang , Peng Zhan , Xinyong Liu . Design, synthesis, and biological evaluation of benzo[4,5]thieno[2,3-d]pyrimidine derivatives as novel HIV-1 NNRTIs. Chinese Chemical Letters, 2024, 35(6): 108827-. doi: 10.1016/j.cclet.2023.108827
3. [3]
  Xiaochun Liu , Gaoyan Chen , Xiaodong Yue , Chaoyue Wang , Xue-Xin Zhang , Xuecheng Ran , Yingxiao Zong , Junke Wang , Xicun Wang . A novel N-stable Co₂P nano-catalyst for the synthesis of quinoxalines by annulation of alkynes and 1,2-diaminobenzenes. Chinese Chemical Letters, 2025, 36(8): 110707-. doi: 10.1016/j.cclet.2024.110707
4. [4]
  Yulong Shi , Fenbei Chen , Mengyuan Wu , Xin Zhang , Runze Meng , Kun Wang , Yan Wang , Yuheng Mei , Qionglu Duan , Yinghong Li , Rongmei Gao , Yuhuan Li , Hongbin Deng , Jiandong Jiang , Yanxiang Wang , Danqing Song . Chemical construction and anti-HCoV-OC43 evaluation of novel 10,12-disubstituted aloperine derivatives as dual cofactor inhibitors of TMPRSS2 and SR-B1. Chinese Chemical Letters, 2024, 35(5): 108792-. doi: 10.1016/j.cclet.2023.108792
5. [5]
  Cheng Huang , Wanqin Zeng , Kunhong Zhong , Xing Duan , Yi Liu , Qingqing Tian , Liangxue Zhou , Yuelong Wang , Chunlai Nie , Aiping Tong . A novel ionizable lipid nanoparticle platform for circular RNA-encoded PD-L1×CD3 bispecific antibodies elicits potent antitumor immunity. Chinese Chemical Letters, 2026, 37(8): 112322-. doi: 10.1016/j.cclet.2025.112322
6. [6]
  Feihu Mu , Benlin Dai , Chuxuan Dai , Xiaozhong Chu , Jiming Xu , Junyu Shen , Wei Zhao , Guohui Dong . Novel 2D/1D MXene/Bi₅O₇I Schottky junction for photocatalytic degradation of bisphenol AF by peroxymonosulfate-assisted photocatalysis. Chinese Chemical Letters, 2026, 37(9): 111866-. doi: 10.1016/j.cclet.2025.111866
7. [7]
  Peiyan Zhu , Yanyan Yang , Hui Li , Jinhua Wang , Shiqing Li . Rh(Ⅲ)‐Catalyzed sequential ring‐retentive/‐opening [4 + 2] annulations of 2H‐imidazoles towards full‐color emissive imidazo[5,1‐a]isoquinolinium salts and AIE‐active non‐symmetric 1,1′‐biisoquinolines. Chinese Chemical Letters, 2024, 35(10): 109533-. doi: 10.1016/j.cclet.2024.109533
8. [8]
  You Zhou , Li-Sheng Wang , Shuang-Gui Lei , Bo-Cheng Tang , Zhi-Cheng Yu , Xing Li , Yan-Dong Wu , Kai-Lu Zheng , An-Xin Wu . I₂-DMSO mediated tetra-functionalization of enaminones for the construction of novel furo[2′,3′:4,5]pyrimido[1,2-b]indazole skeletons via in situ capture of ketenimine cations. Chinese Chemical Letters, 2025, 36(1): 109799-. doi: 10.1016/j.cclet.2024.109799
9. [9]
  Erzhuo Cheng , Yunyi Li , Wei Yuan , Wei Gong , Yanjun Cai , Yuan Gu , Yong Jiang , Yu Chen , Jingxi Zhang , Guangquan Mo , Bin Yang . Galvanostatic method assembled ZIFs nanostructure as novel nanozyme for the glucose oxidation and biosensing. Chinese Chemical Letters, 2024, 35(9): 109386-. doi: 10.1016/j.cclet.2023.109386
10. [10]
  Shaoqing Du , Xinyong Liu , Xueping Hu , Peng Zhan . Targeting novel sites represents an effective strategy for combating drug resistance. Chinese Chemical Letters, 2025, 36(1): 110378-. doi: 10.1016/j.cclet.2024.110378
11. [11]
  Fadeng Yang , Pengli Zhang , Jianbo Liu , Chuan Wan , Jinming Sun , Chuan Dai , Zhihong Liu , Yuhao An , Yujie Wu , Yun Xing , Feng Yin , Yuxin Ye , Wei Han , Zigang Li . Self-assembly of a cyclo-pentapeptide with a novel frame structure. Chinese Chemical Letters, 2025, 36(9): 110785-. doi: 10.1016/j.cclet.2024.110785
12. [12]
  Jun Xiong , Bi-Feng Yuan . PELSA: A novel method for highly sensitive identification of protein targets and binding regions. Chinese Chemical Letters, 2025, 36(12): 111527-. doi: 10.1016/j.cclet.2025.111527
13. [13]
  Xiafeng Yang , Wushan Sun , Chen Li , Wei Bai , Qingyin Wang , Gongying Wang . Synthesis of novel isosorbide-based polycarbonates by melt chain extension method. Chinese Chemical Letters, 2026, 37(4): 111674-. doi: 10.1016/j.cclet.2025.111674
14. [14]
  Peizhang Zhao , Mengmeng Li , Jingwen Wang , Jun Li , Yunfeng Lin . Targeting the immune microenvironment: A novel strategy for treating infected bone defects with hydrogels. Chinese Chemical Letters, 2026, 37(5): 111319-. doi: 10.1016/j.cclet.2025.111319
15. [15]
  Yang Hong , Qianwei Su , Xiang Wu , Qin Zhang , Jianhua Sun , Yu Wang , Jiacan Su . Biocompatible mesoporous silica: A novel nanomaterial for skin wound healing. Chinese Chemical Letters, 2026, 37(8): 111846-. doi: 10.1016/j.cclet.2025.111846
16. [16]
  Anqi Shi , Jiahao Xiang , Qingyun Zhang , Minghui Tan , Wen Xiao , Yang Yang , Lin Zhao , Jian Liu , An Pan , Junwei Wang , Lihong Hu . Discovery of a novel cardiac myosin inhibitor for the treatment of hypertrophic cardiomyopathy. Chinese Chemical Letters, 2026, 37(8): 111786-. doi: 10.1016/j.cclet.2025.111786
17. [17]
  Wu-Jian Long , Yang Yu , Chuang He . A novel and promising engineering application of carbon dots: Enhancing the chloride binding performance of cement. Chinese Chemical Letters, 2024, 35(6): 108943-. doi: 10.1016/j.cclet.2023.108943
18. [18]
  Ting-Ting Huang , Jin-Fa Chen , Juan Liu , Tai-Bao Wei , Hong Yao , Bingbing Shi , Qi Lin . A novel fused bi-macrocyclic host for sensitive detection of Cr₂O₇²⁻ based on enrichment effect. Chinese Chemical Letters, 2024, 35(7): 109281-. doi: 10.1016/j.cclet.2023.109281
19. [19]
  Tiantian Li , Ruochen Jin , Bin Wu , Dongming Lan , Yunjian Ma , Yonghua Wang . A novel insight of enhancing the hydrogen peroxide tolerance of unspecific peroxygenase from Daldinia caldariorum based on structure. Chinese Chemical Letters, 2024, 35(4): 108701-. doi: 10.1016/j.cclet.2023.108701
20. [20]
  Sinong Wang , Shanshan Jin , Xue Yang , Yanyan Huang , Peng Liu , Yi Tang , Yuliang Yang . Development of Mg-Al LDH and LDO as novel protective materials for deacidification of paper-based relics. Chinese Chemical Letters, 2024, 35(9): 109890-. doi: 10.1016/j.cclet.2024.109890