Citation: Hong YU, Fei WANG, Shou Fang ZHANG. Synthesis of 5-Aryl-1, 2-dihydro-1-pyrrolizinones[J]. Chinese Chemical Letters, ;2003, 14(6): 565-568. shu

Synthesis of 5-Aryl-1, 2-dihydro-1-pyrrolizinones

Shenyang Pharmaceutical University, Shenyang 110015

Received Date: 25 July 2002

In order to search for new potent anti-inflammatory and analgesic agents inpyrrolizinones, the title compounds were designed and synthesized. A series of the compoundswere prepared with two different synthetic schemes. Some of the compounds showed remarkableanti-inflammatory and/or analgesic activities on mice.
- 5-Aryl-1,2-dihydro-1-pyrrolizinone,
- anti-inflammation,
- analgesic,
- synthesis
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