Citation: Jia Xi XU, Meng Shen CAI. Mapping the Antigenic Peptides of Sm26/2 in Glutathione STransferases of Schistosoma Mansoni[J]. Chinese Chemical Letters, ;1998, 9(4): 377-379. shu

Mapping the Antigenic Peptides of Sm26/2 in Glutathione STransferases of Schistosoma Mansoni

Jia Xi XU ^a ,
Meng Shen CAI ^b

a College of Chemistry and Molecular Engineering, Peking University, Beijing 100871;
b School of Pharmaceutical Sciences, Beijing Medical University, Beijing 100083

Received Date: 1 December 1997

Fund Project: Project 29772002 was supported by National Natural Science Foundation of China.

Six antigenic peptides of Sm26/2 glutathione S-transferase of schistosoma mansoni have been predicted according to their hydrophilicity, flexibility, accessibility, charge distribution and β-turn in the secondary structure by the determination of its primary structure, and synthesized by solid phase method. Two of them showed good antigenicity by Dot-ELISA. They would be candidate peptides of synthetic anti-schistosomal vaccine.
- schistosoma mansoni,
- glutathione S-transferase,
- antigenic peptide,
- peptide vaccine
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