Citation:
Cheng Lu ZHANG, Ying Ge MA, Chun Li SUN, Ye Hong QIU. First Total Synthesis of (±)-13-Hydroxy-8 (14)-abietene[J]. Chinese Chemical Letters,
;2005, 16(6): 727-728.
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The first total synthesis of (±)-13-hydroxy-8 (14)-abietene was accomplished in 20.1%yield via a strategy of AC→ABC, in which the reduction of compound 5 with Li/NH3 gave the key intermediate 6 and the title compound was then obtained by the reaction of compound 6 with Grignard reagent.
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Keywords:
- Total synthesis,
- (±)-13-hydroxy-8(14)-abietene,
- diterpene
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