Citation: Chao CHEN, Yuan Xin TIAN, Xiao Yong ZOU, Pei Xiang CAI, Jin Yuan MO. A Cooperative Approach for the Extraction of Protein Motifs[J]. Chinese Chemical Letters, ;2006, 17(5): 707-710. shu

A Cooperative Approach for the Extraction of Protein Motifs

School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275

Received Date: 23 November 2005

Fund Project: This work was supported by the National Natural Science Foundation of China (No.20475068, 20575082), the Natural Science Foundation of Guangdong Province (No.031577) and the Scientific Technology Project of Guangdong Province (No.2005B30101003).

By integrating the concept of cooperative approach, an extension of the fast annealing coevolutionary algorithm is presented in this paper. It outperformed the original algorithm in the domain of function optimization, especially in terms of convergence rate. It was also applied to a real optimization problem, protein motif extraction. And a satisfactory result has been obtained with the accuracy of prediction achieving 67.0%, which is in agreement with the result in the PROSITE database.
- Cooperative approach,
- global optimization,
- protein motifs extraction
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