Citation: Meng Yuzhang, Gao Yuxia, Ju Yong, Hu Jun. Natural Pentacyclic Triterpene-based Organic Functional Molecules[J]. Chemistry, ;2020, 83(4): 318-324. shu

Natural Pentacyclic Triterpene-based Organic Functional Molecules

  • Corresponding author: Hu Jun, jhu@mail.buct.edu.cn
  • Received Date: 6 December 2019
    Accepted Date: 16 December 2019

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  • Terpenes, isolated from plants and animals, have been widely found in nature. They can be divided into cyclic-, linear-, and polycyclic terpenes according to the number of isoprene units and skeleton rings in their molecular structures. Among them, natural triterpenes are one of the ideal building blocks in the fabrication of functional molecules and show great potentials in the areas of supramolecular chemistry, smart materials, interface chemistry, and drug delivery, due to their advantages in structure and performance like rigid chiral backbone, multiple reactive sites, unique self-assembly ability, good biocompatibility and bioactivity. Glycyrrhetinic acid (GA) and glycyrrhizic acid (GL), two of the classic pentacyclic triterpenes, have attracted considerable attention in the synthesis of organic functional molecules in the past decade. In this paper, we focus on the recent progress of glycyrrhetinic acid/glycyrrhizic acid-derived small molecules and polymers, including design, synthesis, and applications in hydrogels, organogels, hybrid gels, chiral materials, thermo-and self-healable materials, agricultural Pickering-emulsions and polypseudorotaxanes.
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