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Citation: Zhang Chao, Xu Dongdong, Wang Jingjing, Kang Congmin. An Improved Synthesis of Benzothiazole-2-carbaldehyde[J]. Chemistry, ;2017, 80(8): 789-791. shu

An Improved Synthesis of Benzothiazole-2-carbaldehyde

College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042

Corresponding author: Kang Congmin, lvyingtao@qust.edu.cn
Received Date: 10 January 2017
Accepted Date: 28 April 2017

Figures(1)

Benzothiazol-2-yl-methanol was synthesized by the reaction of 2-aminothiophenol with glycolic acid, and then was oxidized to give benzothiazole-2-formaldehyde. By comparing the effects of several oxidants, manganese dioxide was selected as the appropriate agent for the oxidation reaction, and the influence of feed ratio of the raw materials and reaction time on the yield of the product were also studied. The optimum oxidation reaction conditions were as follows: molar ratio of benzothiazol-2-yl-methanol to manganese dioxide is 1:8, reaction time is 8 h. The yield can reach 90.2%. This synthetic route is suitable for the industrial production of titled compound and its derivatives.
- Benzothiazol-2-yl methanol,
- Oxidation,
- Manganese dioxide,
- Benzothiazole-2-carbaldehyde
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