Citation: Mao Weiwei, Wei Xiaohong, You Jinkun, Zhang Hongyan. Progress in Electrochemical Aptamer Biosensors for the Detection of Ochratoxin A[J]. Chemistry, ;2020, 83(12): 1081-1088. shu

Progress in Electrochemical Aptamer Biosensors for the Detection of Ochratoxin A

College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, 350122

Corresponding author: Zhang Hongyan, 38516098@qq.com
Received Date: 30 June 2020
Accepted Date: 30 August 2020

Figures(4)

Ochratoxin is a kind of secondary metabolites mainly produced by aspergillus and penicillium. Ochratoxin A (OTA) is the most toxic one which can cause serious harm to human body. Moreover, it is difficult to be destroyed by conventional food processing because of its high stability. Sensitive and rapid detection of OTA is the key to early detection and treatment of OTA contamination. So far, aptamers have been employed as substitutes for antibodies to construct OTA electrochemical biosensors due to their unique advantages. The classic OTA detection methods and electrochemical aptamer biosensors (aptasensors) were introduced respectively in this paper. Besides, the latest research status of the OTA electrochemical aptasensors were summarized including the optimization of aptamer, the applications of new materials and biomagnification technologies. Meantime, the future development was prospected with the aim of providing some reference for the further research and application of OTA aptasensors.
- Ochratoxin A,
- Aptamer,
- Biosensor,
- Electrochemistry
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