Citation: Tao PENG, Chu Yi YU, Zhi Tang HUANG. Solid-phase Synthesis of a Novel Kind of Hydroxylated Heterocyclic Ketene Aminals[J]. Chinese Chemical Letters, ;2006, 17(11): 1451-1453. shu

Solid-phase Synthesis of a Novel Kind of Hydroxylated Heterocyclic Ketene Aminals

1.
Beijing National Laboratory for Molecular Science(BNLMS), Laboratory for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080;
2.
Graduate University of The Chinese Academy of Sciences, Beijing 100049

Received Date: 28 June 2006

An efficient solid-phase synthesis method for novel heterocyclic ketene aminals containing a hydroxyl group has been developed. The loading of the substrate on the resin through the hydroxyl group and the protection of the amine by the Schiff base were the key steps in the synthesis.
- Solid-phase synthesis,
- Schiff base,
- hydroxylated,
- heterocyclic ketene aminals
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