Citation: Yong WU, Mei GUAN. The Synthesis of an Optically Active Intermediate of A-Ring for1α,25-Dihydroxy Vitamin D3 Analogs[J]. Chinese Chemical Letters, ;1998, 9(5): 431-432. shu

The Synthesis of an Optically Active Intermediate of A-Ring for1α,25-Dihydroxy Vitamin D3 Analogs

Yong WU ¹ ,
Mei GUAN ²

1.
School of Pharmacy, West China University of Medical Sciences, Chengdu 610041;
2.
The First Hospital, West China University of Medical Sciences, Chengdu 610041

Received Date: 30 December 1997

Synthesis of an optically active intermediate 4b for the A-ring of 1α,25-dihydroxyvitamin D₃ analogs has been achieved in eight steps, starting from readily available, inexpensive D-(+)-xylose.
- 1α,25-dihydroxyvitamin D₃,
- D(+)-xylose,
- synthesis
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