Citation: Hao Feng YU, Guo Qi FU, Li LIU, Bing Lin HE. Facile Synthesis and Adsorption Properties of Phosphonated Cellulose Beads for Selective Removal of Low-density Lipoprotein[J]. Chinese Chemical Letters, ;2006, 17(9): 1193-1196. shu

Facile Synthesis and Adsorption Properties of Phosphonated Cellulose Beads for Selective Removal of Low-density Lipoprotein

The Key Laboratory of Functional Polymer Materials of Ministry of Education, Institute of Polymer Chemistry, Nankai University, Tianjin 300071

Received Date: 3 April 2006

Fund Project: This work was supported by the National Key Project of Fundamental Research (G1999064707).

A novel low-density lipoprotein adsorbent was prepared simply by directly phosphonating porous cellulose beads. Tests in vitro demonstrated that this adsorbent showed quite good adsorption performance for selective removal of low-density lipoprotein from human plasma. The effects of preparation conditions on the lipoprotein sorption properties of the resulted adsorbent were investigated. The adsorption dynamics was also examined.
- Cellulose beads,
- phosphonation,
- low-density lipoprotein,
- adsorption,
- hyperlipemia
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