Citation: Li Min GUO, Wen Juan DONG, Chuan DONG. Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence[J]. Chinese Chemical Letters, ;2006, 17(2): 253-254. shu

Study on the Interaction of Pd-TMPyP with ctDNA by Solid-substrate Room Temperature Phosphorescence

School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006

Received Date: 22 June 2005

Fund Project: This work was supported by the National Natural Science Foundation of China (No.20275022).

The interaction between calf thymus DNA (ctDNA) and Pd (Ⅱ) meso-tetrakis(4-N-methyl pyridiniumyl) porphyrin (Pd-TMPyP) was investigated by steady solid-substrate room temperature phosphorescence (SS-RTP). The SS-RTP intensity and lifetime of Pd-TMPyP enhanced with the increasing ctDNA. The anion quenching experiment of Pd-TMPyP indicated that Pd-TMPyP intercalated into ctDNA, which was also approved by UV-Vis spectra.
- Pd-TMPyP,
- ctDNA,
- SS-RTP,
- intercalation
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