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Citation: Dai Lerong, Yang Qingping, Wu Peiqiang. Solubilization of Cholesterol in Polyoxyethylene Ether Lyotropic Liquid Crystal[J]. Chinese Journal of Applied Chemistry, ;1996, 13(3): 41-45. shu

Solubilization of Cholesterol in Polyoxyethylene Ether Lyotropic Liquid Crystal

1.
Institute of Physical Chemistry, Peking University, Beijing 100871

Received Date: 26 September 1995
Available Online: 31 December 1995
Fund Project:

Phase behaviour and solubilization of cholesterol in liquid crystal phase of C₁₂(EO)₄-H₂O system and C₁₂(EO)₄-lecithin-H₂O system were investigated.The phase diagram of C₁₂(EO)₄-lecithin-water-cholesterol system was similar to lecithin-water-cholesterol system.In C₁₂(EO)₄-H₂O ststem,where cholesterol was solubilized,the concentration range of C₁₂(EO)₄ in liquid crystal was broader than that without cholesterol.The results of X-ray diffraction showed that,when cholesterol was solubilized into C₁₂(EO)₄-H₂O lamellar liquid crystal,the thickness of amphiphile bilayer d₀ increased,the amphiphile molecular array was more compact and the penetration of water molecules decreased.
- polyoxyethylene ether,
- lyotropie liquid erystal,
- eholesterol,
- solubilization
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