Citation: Yin Xiaogang, Wu Xiaoyun, Wang Ye, Chen Zhiming, Chen Zhuo. Biginelli Reaction Catalysized by I₂ Loaded Montmorillonite under Ultrasonic Condition[J]. Chemistry, ;2016, 79(9): 834-838. shu

Biginelli Reaction Catalysized by I₂ Loaded Montmorillonite under Ultrasonic Condition

1.
Key Laboratory of Functional Materials Chemistry of Guizhou Province, School of Chemistry and Materials Science, Guizhou Normal University, Guiyang 550001

Corresponding author: Chen Zhuo,
Received Date: 7 January 2016
Available Online: 18 May 2016
Fund Project:

An ultrasound-assisted Biginelli reaction catalysized by I₂ loaded montmorillonite was developed using ethylacetoacetate, aromatic aldehyde and urea as starting materials. Influences of solvents, catalysts on the yield were investigated using single factor methods, and the temperature, ultrasonic time, equivalent ratio of starting materials were screened using orthogonal tests. Under the optimized conditoin, the yields of 3,4-dihydropyrimidin-2(1H)one derivatives were up to 86.9%. The products were characterized by ¹H NMR, IR and m.p.
- Montmorillonite,
- I₂,
- Ultrasonic assisted,
- Biginelli reaction
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Biginelli Reaction Catalysized by I2 Loaded Montmorillonite under Ultrasonic Condition

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通讯作者: 陈斌, bchen63@163.com

Biginelli Reaction Catalysized by I₂ Loaded Montmorillonite under Ultrasonic Condition