引用本文:
孙卫东, 高飞飞, 张锁秦, 李耀先, 张广良. 新型2-乙内酰硫脲衍生物的合成与表征[J]. 应用化学,
2006, 23(5): 538-542.
Citation: SUN Wei-Dong, GAO Fei-Fei, ZHANG Suo-Qin, LI Yao-Xian, ZHANG Guang-Liang. Synthesis and Characterization of Novel 2-Thiohydantoin Derivatives[J]. Chinese Journal of Applied Chemistry, 2006, 23(5): 538-542.
Citation: SUN Wei-Dong, GAO Fei-Fei, ZHANG Suo-Qin, LI Yao-Xian, ZHANG Guang-Liang. Synthesis and Characterization of Novel 2-Thiohydantoin Derivatives[J]. Chinese Journal of Applied Chemistry, 2006, 23(5): 538-542.
新型2-乙内酰硫脲衍生物的合成与表征
English
Synthesis and Characterization of Novel 2-Thiohydantoin Derivatives
Abstract:
Novel 2-thiohydantoin derivatives were synthesized,and the structures of the title compounds were confirmed by 1H NMR,13C NMR,and IR.The preliminary biological tests of the title compounds were carried out.The structure-activity relationship was analyzed from structure characteristic and substituent effect.The results show that 5-methyl-2-thiohydantoin derivatives exhibit higher biological activity than those without 5-methyl.The maximum inhibiting rate is 56.5%(sprout) and 53.8%(root).2-Thiohydantoin derivatives can be made into novel pesticide precursor compounds.
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Key words:
- acetohydroxyacid synthase
- / sulfonylurea
- / thiohydantoin
- / synthesis
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