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Citation: YUE Ke-Fen, ZHOU Chun-Sheng, JIANG Yan-Mei. A Novel Synthetic Method for Phenylacetaldehyde and p-Methoxybenzaldehyde[J]. Chinese Journal of Applied Chemistry, ;2008, 25(9): 1113-1115. shu

A Novel Synthetic Method for Phenylacetaldehyde and p-Methoxybenzaldehyde

1.
a MOE Key Laboratory of Synthetic and Natural Functional Molecule Chemistry, Department of Chemistry, Northwest University, Xi'an 710069;
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b Department of Chemistry, Shangluo Normal College, Shangzhou

Corresponding author: YUE Ke-Fen,
Received Date: 21 October 2007
Available Online: 10 March 2008
Fund Project: 西北大学基金(02NW15)资助项目 (02NW15)

1,3-Dimethyl-2-substituted benzimidazolium salts can be easily prepared from phenylacetate or p-methoxybenzoic acid,o-phenylenediamine and methyl iodide via cyclization and quarternarization.Phenylacetaldehyde and p-methoxylbenzaldehyde were respectively prepared through the reduction-hydrolysis reaction of the corresponding 1,3-dimethyl-2-substituted benzimidazolium ioidide with sodium hydrogen telluride.A novel synthetic method for phenylacetaldehyde or p-methoxylbenzaldehyde from phenylacetate or p-methoxybenzoic acid via reduction-hydrolysis of benzimidazolium salt is presented.This synthetic route has mild reaction conditions and high product purities.The reaction mechanism is discussed.
- phenylacetaldehyde,
- p-methoxylbenzaldehyde,
- sodium hydrogen telluride,
- dimethylsubstituted benzimidazolium ioidide
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