浅谈2014年诺贝尔化学奖:超高分辨率荧光显微成像

孙育杰 陈轩泽

引用本文: 孙育杰, 陈轩泽. 浅谈2014年诺贝尔化学奖:超高分辨率荧光显微成像[J]. 大学化学, 2015, 33(1): 1-9. shu
Citation:  Sun Yujie, Chen Xuanze. Nobel Prize in Chemistry 2014: Super-resolved Fluorescence Microscopy[J]. University Chemistry, 2015, 33(1): 1-9. shu

浅谈2014年诺贝尔化学奖:超高分辨率荧光显微成像

    通讯作者: 孙育杰
  • 基金项目:

    国家青年千人计划 

    基金委重大仪器设备研发专项(No.31327901) (No.31327901)

摘要: 超分辨显微成像技术是近些年来发展最快、受关注度最高的光学成像技术之一。这类技术突破了光学衍射极限,将显微镜的分辨率从几百纳米提高到几十纳米,为生命科学研究提供了一个强大工具。目前主流的超分辨率显微技术主要基于点扩散函数调制和单分子定位的原理来实现。其主要贡献者也成为2014年诺贝尔化学奖的获得者。本文简要讲述超分辨显微技术的发展历程并对其发展趋势进行展望。

English

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